4553-59-7

Basic information

• Product Name: PHENYL-PHENYLAMINO-ACETONITRILE
• Synonyms: PHENYL-PHENYLAMINO-ACETONITRILE;anilino(phenyl)acetonitrile;2-(Phenylamino)-2-phenylacetonitrile;2-Anilino-2-phenylacetonitrile;N,2-Diphenylglycinonitrile;α-(Phenylamino)benzeneacetonitrile;α-Anilinobenzeneacetonitrile;2-phenyl-2-(phenylaMino)acetonitrile
• CAS NO: 4553-59-7
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.26
• Mol File: 4553-59-7.mol
• Article Data: 178

Chemical Properties

• Boiling Point: 369.7°Cat760mmHg
• Flash Point: 177.4°C
• Appearance: /
• Density: 1.155g/cm³
• Vapor Pressure: 1.17E-05mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: PHENYL-PHENYLAMINO-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL-PHENYLAMINO-ACETONITRILE(4553-59-7)
• EPA Substance Registry System: PHENYL-PHENYLAMINO-ACETONITRILE(4553-59-7)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 4553-59-7(Hazardous Substances Data)

Usage

General Description

PHENYL-PHENYLAMINO-ACETONITRILE, also known as 2-phenylbenzylamine or benzylphenylamine, is a chemical compound with the molecular formula C14H12N2. It is a white solid that is commonly used in the synthesis of pharmaceuticals and organic compounds. PHENYL-PHENYLAMINO-ACETONITRILE is a derivative of acetophenone with a phenylamino group attached to the acetonitrile moiety. It is often used as a building block in organic synthesis for the preparation of various compounds, including pharmaceuticals, agrochemicals, and dyes. Additionally, it is also utilized in the production of rubber chemicals and as an intermediate in the manufacture of other organic compounds.

InChI:InChI=1/C14H12N2/c15-11-14(12-7-3-1-4-8-12)16-13-9-5-2-6-10-13/h1-10,14,16H

Upstream product

• 74-90-8 hydrogen cyanide 
• 538-51-2 benzylidene phenylamine 
• 60-29-7 diethyl ether 
• 151-50-8 potassium cyanide 
• 142-04-1 aniline hydrochloride 
• 100-52-7 benzaldehyde 
• 64-17-5 ethanol 
• 62-53-3 aniline 
• 71-43-2 benzene 
• 532-28-5 (RS)-mandelonitrile 
• 127-09-3 sodium acetate 
• 46887-57-4 1-phenyl-1-phenylaminomethanesulfonic acid 
• 7677-24-9 trimethylsilyl cyanide 
• 86712-42-7 2,3-dianilino-2,3-diphenyl-propionitrile 

Downstream Products

• 52240-29-6 (1-methyl-2-oxo-2-phenyl-ethyl)-malonic acid 
• 861384-66-9 5-cyano-4-methyl-2-oxo-1,5-diphenyl-pyrrolidine-3-carboxylic acid 
• 6932-23-6 1,2,3,4-tetraphenyl-1H-pyrrole 
• 857424-42-1 5-hydroxy-1,2,3-triphenyl-5-styryl-pyrrolidine-2-carbonitrile 
• 86712-42-7 2,3-dianilino-2,3-diphenyl-propionitrile 
• 74-90-8 hydrogen cyanide 
• 2879-66-5 N,N',1,2-tetraphenylethylenediamine 
• 538-51-2 benzylidene phenylamine 
• 62-53-3 aniline 
• 42164-54-5 N-(2-amino-1-phenylethyl)benzenamine 
• 60561-61-7 α-anilino-α-phenylacetamide 
• 51444-33-8 anilino-phenyl-thioacetic acid amide 
• 101350-25-8 (N-acetyl-anilino)-phenyl-acetonitrile 
• 14062-91-0 (N-benzoyl-anilino)-phenyl-acetonitrile 

Relevant articles and documents

Use of polyazaheterocycles in the assembly of new cadmium sulfate frameworks: Synthesis, structure, and properties

The reaction of cadmium sulfate in the presence of polyazaheterocyclic organic molecules gave rise to a variety of new cadmium sulfate phases in water containing solvothermal reaction. The compounds have two- (I) and three-dimensionally (II-VI) extended s

Aliphatic amine mediated assembly of [M6(mna)6] (M = Cu/Ag) into extended two-dimensional structures: synthesis, structure and Lewis acid catalytic studies

Two new two-dimensional layered compounds, [{Ag6(2-mna)6Cd(Hen)2}{Cd(en)22H2O}(H2O)8],I, and [{M6(2-mna)6Cd(Hen)2}(H2en)(H2

Synthesis and characterization of Pd supported on methane diamine (propyl silane) functionalized Fe3O4 nanoparticles as a magnetic catalyst for synthesis of α-aminonitriles and 2-methoxy-2-phenylacetonitrile derivative via Strecker-t

Pd supported on methane diamine (propyl silane) functionalized Fe3O4 magnetic nanoparticles as an organic–inorganic hybrid heterogeneous catalyst was fabricated and characterized by FT-IR, XRD, SEM, TEM, TGA, VSM, EDX, and ICP-AES te

Cd-MOF@PVDF Mixed-Matrix Membrane with Good Catalytic Activity and Recyclability for the Production of Benzimidazole and Amino Acid Derivatives

Mixed-matrix membranes (MMMs) incorporating metal-organic framework crystalline fillers as heterogeneous catalysts for organic transformation reactions have attracted more attention in catalysis science. Herein, a new 3D cadmium metal-organic framework (H3O)·[Cd(dppa)] (1) was first synthesized using the rigid 4-(3,5-dicarboxylphenyl)picolinic acid (H3dppa) as an organic ligand under solvothermal conditions, exhibiting a novel 6,6-connected network and good tolerance to various solvents. After activation, 1 showed good catalytic reactivity and selectivity for the synthesis of benzimidazole derivatives, affording solvent-dependent catalytic activity. Then, using the microcrystals of 1 and poly(vinylidene fluoride) (PVDF) as raw materials, 1@PVDF MMMs were successfully prepared by polymer solution casting. Notably, the integration of MOF and PVDF endows the mixed-matrix membrane 1@PVDF with great advantages in terms of more dispersive Lewis acid catalytic sites and recyclability. As expected, 1@PVDF not only displays good catalytic activity comparable to that of activated 1 but also exhibits remarkable recyclability and continuous usability for the production of benzimidazole and α-or β-amino acid derivatives. To the best of our knowledge, this is the first time that a Cd-based MOF and MMMs have been applied as a catalyst for the production of a β-amino acid. The combination of catalytic MOF and PVDF provides a way to simplify the design of a flow reactor and reduce the costs of manufacturing.