464216-16-8

Basic information

• Product Name: 3-Pyridinecarboxylicacid,2-amino-,1,1-dimethylethylester(9CI)
• Synonyms: 3-Pyridinecarboxylicacid,2-amino-,1,1-dimethylethylester(9CI);tert-butyl 2-aminonicotinate
• CAS NO: 464216-16-8
• Molecular Formula: C₁₀H₁₄N₂O₂
• Molecular Weight: 194.23
• Product Categories: AMINOACID
• Mol File: 464216-16-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarboxylicacid,2-amino-,1,1-dimethylethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylicacid,2-amino-,1,1-dimethylethylester(9CI)(464216-16-8)
• EPA Substance Registry System: 3-Pyridinecarboxylicacid,2-amino-,1,1-dimethylethylester(9CI)(464216-16-8)

Safety Data

• Hazardous Substances Data: 464216-16-8(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 91-01-0 1,1-Diphenylmethanol 
• 122-97-4 3-Phenyl-1-propanol 
• 2216-51-5 (-)-menthol 
• 111-26-2 hexan-1-amine 
• 4045-24-3 4-methoxypiperidine 
• 71-23-8 propan-1-ol 
• 645-09-0 3-nitrobenzamide 
• 232951-83-6 tert-butyl 2-chloropyridine-3-carboxylate 

Downstream Products

• 232951-83-6 tert-butyl 2-chloropyridine-3-carboxylate 
• 37787-77-2 Boc-L-proline benzyl ester 

Relevant articles and documents

PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS

The present invention relates to a catalytic method for the conversion of amide-containing compouds by means of a build-in directing group and upon the action of a heteronucleophilic compound (in se an amine (RNH2 or RNHR') or an alcohol (ROH) or a thiol (RSH)) in the presence of a metal catalyst to respectively esters, thioesters, carbonates, thiocarbonates and to what is defined as amide-containing compounds (such as carboxamides, urea, carbamates, thiocarbamates). The present invention also relates to these amide-containing compounds having a build-in directing group (DG), as well as the use of such directing groups in the catalytic directed cleavage of N-DG amides with the use of heteronucleophiles (in se an amine (RNH2 or RNHR') or an alcohol (ROH) or thiol (RSH)).