4655-89-4

Basic information

• Product Name: 3,4-Dihydro-2,2-dimethyl-5-methoxy-8-acetyl-2H-1-benzopyran-7-ol
• Synonyms: (7-Hydroxy-5-methoxy-2,2-dimethylchroman-8-yl)(methyl) ketone;1-(3,4-Dihydro-7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-8-yl)ethanone;3,4-Dihydro-2,2-dimethyl-5-methoxy-8-acetyl-2H-1-benzopyran-7-ol;Dihydroalloevodionol
• CAS NO: 4655-89-4
• Molecular Formula: C₁₄H₁₈O₄
• Molecular Weight: 0
• Mol File: 4655-89-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-Dihydro-2,2-dimethyl-5-methoxy-8-acetyl-2H-1-benzopyran-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dihydro-2,2-dimethyl-5-methoxy-8-acetyl-2H-1-benzopyran-7-ol(4655-89-4)
• EPA Substance Registry System: 3,4-Dihydro-2,2-dimethyl-5-methoxy-8-acetyl-2H-1-benzopyran-7-ol(4655-89-4)

Safety Data

• Hazardous Substances Data: 4655-89-4(Hazardous Substances Data)

Upstream product

• 32541-38-1 1-(5,7-dihydroxy-2,2-dimethyl-chroman-8-yl)-ethanone 
• 74-88-4 methyl iodide 
• 484-18-4 1-(7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-ethanone 
• 50386-17-9 3,4-Dihydro-7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran 
• 64-19-7 acetic acid 
• 77-78-1 dimethyl sulfate 
• 125116-28-1 Acetic acid 5-methoxy-2,2-dimethyl-chroman-7-yl ester 
• 7507-89-3 2,6-dihydroxy-4-methoxy-acetophenone 
• 78-79-5 isoprene 
• 115-18-4 2-methyl-3-buten-2-ol 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 29373-14-6 2,2-dimethylchromane-5,7-diol 
• 870-63-3 prenyl bromide 
• 77179-30-7 1-(2,6-dihydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)phenyl)ethan-1-one 

Downstream Products

• 50678-96-1 5-methoxy-2,2-dimethyl-8-phenyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-10-one 
• 68634-30-0 5-methoxy-8-(4-methoxy-phenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-10-one 
• 135940-07-7 8-(3,4-Dimethoxy-phenyl)-5-methoxy-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-10-one 
• 88055-39-4 9-Hydroxy-8-(4'-methoxyphenyl)-5-methoxy-2,2-dimethyl-3,4-dihydro-2H,10H-benzo<1,2-b:3,4-b'>dipyran-10-one 
• 86978-01-0 4-Methoxy-benzoic acid 8-acetyl-5-methoxy-2,2-dimethyl-chroman-7-yl ester 
• 88055-41-8 9-Hydroxy-8-(3',4'-dimethoxyphenyl)-5-methoxy-2,2-dimethyl-3,4-dihydro-2H,10H-benzo<1,2-b:3,4-b'>dipyran-10-one 
• 484-18-4 1-(7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-ethanone 
• 143725-44-4 5-Methoxy-8-(4-methoxy-phenyl)-2,2-dimethyl-2H-pyrano[2,3-f]chromen-10-one 
• 86978-02-1 1-(7-Hydroxy-5-methoxy-2,2-dimethyl-chroman-8-yl)-3-(4-methoxy-phenyl)-propane-1,3-dione 
• 85526-78-9 1-(7-hydroxy-5-methoxy-2,2-dimethyl-chroman-8-yl)-3-phenyl-propan-1-one 

Relevant articles and documents

Mallotojaponins B and C: Total Synthesis, Antiparasitic Evaluation, and Preliminary SAR Studies

(Chemical Equation Presented). The first total syntheses of mallotojaponin B and C as well as several analogues have been achieved. Biological evaluation of the synthesized compounds against Plasmodium falciparum and Trypanosoma brucei have also been carried out.

Heterocycles: Part 7 - Synthesis of acetyl hydroxy-2,2-dimethylchromans

Synthesis of acetyl hydroxy-2,2-dimethylchromans by two methods namely photo-Fries rearrangement of acetoxy-2,2-dimethylchromans (UV light, 253.7 nm) and Friedel-Crafts acetylation of hydroxy-2,2-dimethylchromans with gl. acetic acid using AlCl3/POCl3 has been described.

ACID-CATALYZED CONDENSATION OF ISOPRENE AND 2-METHYLBUT-3-EN-2-OL WITH PHLOROACETOPHENONE, NEW SYNTHESIS OF ALLOEVODIONOL AND FRANKLINONE

The naturally occurring acetylchromenes, alloevodionol (1) and franklinone (2) have been synthesized by the nuclear isoprenylation of phloroacetophenone followed by the partial methylation and dehydrogenation of the chromans thus obtained.