7507-89-3

Basic information

• Product Name: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE
• Synonyms: 1-(2,6-Dihydroxy-4-methoxyphenyl)ethanone , Tech.;4-O-Methylphloroacetophenone;NSC 401443;4-O-Methylphloracetophenone;Acetophenone, 2',6'-dihydroxy-4'-methoxy-;Ethanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-;2',6'-DIHYDROXY-4'-METHOXYACETOPHENONE;1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE
• CAS NO: 7507-89-3
• Molecular Formula: C₉H₁₀O₄
• Molecular Weight: 182.17
• Product Categories: Aromatic Acetophenones & Derivatives (substituted)
• Mol File: 7507-89-3.mol
• Article Data: 24

Chemical Properties

• Melting Point: 144 °C
• Boiling Point: 356.7 °C at 760 mmHg
• Flash Point: 146.3 °C
• Appearance: /
• Density: 1.284 g/cm³
• PKA: 9.27±0.15(Predicted)
• CAS DataBase Reference: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE(7507-89-3)
• EPA Substance Registry System: 1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE(7507-89-3)

Safety Data

• Hazardous Substances Data: 7507-89-3(Hazardous Substances Data)

Usage

Preparation

Obtained by reaction of boiling aqueous potassium hydroxide, ? on the Methyl 3-acetyl-2,4-dihydroxy-6-methoxybenzoate (quantitative yield) ; ? on the 3-trichloroacetyl-2,6-dihydroxy-4-methoxyacetophenone.

Upstream product

• 186581-53-3 diazomethane 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 412036-13-6 3-acetyl-2,4-dihydroxy-6-methoxy-benzoic acid methyl ester 
• 412036-66-9 2-acetyl-5-methoxy-4-trichloroacetyl-resorcinol 
• 832-58-6 1-(2,4,6-trimethoxyphenyl)ethanone 
• 63013-34-3 2,6-dihydroxy-4-methoxyacetophenone 2-O-β-D-gentiobioside 
• 77-78-1 dimethyl sulfate 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 480-34-2 eugenin 
• 521-34-6 sciadopitysin 
• 481-46-9 ginkgetin 
• 10378-90-2 2,4-dihydroxy-6-methoxy-benzoic acid methyl ester 
• 720698-36-2 2,2,2-trichloro-1-(2,4-dihydroxy-6-methoxy-phenyl)-ethanone 

Downstream Products

• 24587-98-2 2',6'-dihydroxy-4'-methoxyacetophenone 2'-O-(2,3,4,6-O-tetraacetyl)-β-D-glucopyranoside 
• 136258-09-8 2'-hydroxy-4'-methoxy-6'-tetrahydropyranyloxyacetophenone 
• 136258-10-1 2',6'-dihydroxy-4'-methoxy-3'-tetrahydropyranylacetophenone 
• 77179-30-7 1-(2,6-dihydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)phenyl)ethan-1-one 
• 3818-99-3 10-acetyl-3,4,6,7-tetrahydro-5-methoxy-2,2,8,8-tetramethyl-2H,8H-benzo<1,2-b:5,4-b'>dipyran 
• 4655-89-4 8-Acetyl-7-hydroxy-5-methoxy-3,4-dihydro-2,2-dimethyl-2H-<1>benzopyran 
• 23937-88-4 1-{2-[3-(2-Acetyl-3-hydroxy-5-methoxy-phenoxy)-2-hydroxy-propoxy]-6-hydroxy-4-methoxy-phenyl}-ethanone 
• 76554-79-5 1-(2-ethoxy-6-hydroxy-4-methoxy-phenyl)-ethanone 
• 7507-87-1 2-Acetyl-3-hydroxy-5-methoxy-[1,4]benzochinon 
• 14218-44-1 <2-Acetyl-3-hydroxy-5-methoxy-phenoxy>-essigsaeure-ethylester 
• 66568-98-7 5,4'‐dihydroxy‐7,3'‐dimethoxyflavanone 
• 93012-86-3 7-methoxy-3',4',5-trihydroxyflavanone 
• 186693-85-6 1-[2-hydroxy-4-methoxy-6-(methoxymethoxy)phenyl]ethan-1-one 
• 81719-04-2 4,2',6'-trihydroxy-4'-methoxychalkone 

Relevant articles and documents

Structure of pleoside from Pleopeltis thunbergiana]

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Structural elucidation, total synthesis, and cytotoxic activity of effphenol A

A highly substituted phenol derivative, effphenol A (1), was isolated from the deep-sea-derived fungus Trichobotrys effuse FS524. Its complete structural assignment was established through a combination of spectroscopic analysis together with single-crystal X-ray diffraction experiments and further unequivocally confirmed by a biomimetic total synthesis. Structurally, effphenol A possesses a poly-substituted 6-5/6/6 tetracyclic ring system, which represents the first case of such a skeleton found in nature. Furthermore, the cytotoxic activity of effphenol A (1) toward four human cancer cell lines was assayed. This journal is

Process for preparing flavonoid derivatives and the intermediate thereof

The present invention provides: a method for manufacturing a flavonoid derivative using a reaction for synthesizing a chalcone derivative by a protection/deprotection reaction of a hydroxyl group and an aldol condensation reaction; and an intermediate thereof. By the method for manufacturing the flavonoid derivative of the present invention can manufacture the flavonoid derivative such as velutin and homoeriodictyol, the present invention can be usefully used in industrial fields such as cosmetics requiring mass production of flavonoid derivatives.