4664-73-7 Usage
Structure
Cyclohexanecarboxamide derivative with a chlorine atom and a phenyl group attached to the nitrogen atom
Physical state
White crystalline solid
Solubility
Insoluble in water, soluble in organic solvents
Applications
Intermediate in the synthesis of pharmaceuticals and agrochemicals
Functional groups
Amide functional group
Reactivity
Suitable for use as a coupling agent in organic reactions
Check Digit Verification of cas no
The CAS Registry Mumber 4664-73-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,6 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4664-73:
(6*4)+(5*6)+(4*6)+(3*4)+(2*7)+(1*3)=107
107 % 10 = 7
So 4664-73-7 is a valid CAS Registry Number.
4664-73-7Relevant articles and documents
Dichloromethane as a chlorination reagent for α-bromocarbonyl compounds in the presence of a copper catalyst
Takeuchi, Kentaro,Ishida, Syo,Nishikata, Takashi
supporting information, p. 644 - 646 (2017/08/30)
We found that dichloromethane is a powerful chlorinating reagent for the congested 3° and 2° Csp3Br bond of α-bromocarbonyl amides, esters, and ketones. In the presence of an appropriate copper complex as a catalyst, the desired chlorination occurred within an hour. Control experiments revealed that in situ-generated CuCl2 is a key chlorinating agent that reacts with the 3° or 2° alkyl radicals generated by the reaction between an α-bromocarbonyl compound and a Cu(I) salt.