4687-24-5

Basic information

• Product Name: Benzofuran-3-carboxylic acid methyl ester
• Synonyms: 3-Benzofurancarboxylic acid methyl ester;Benzofuran-3-carboxylic acid methyl ester;3-BENZOFURANCARBONYL CHLORIDE, METHYL ESTER
• CAS NO: 4687-24-5
• Molecular Formula: C₁₀H₈O₃
• Molecular Weight: 176.17
• Mol File: 4687-24-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 257.7±13.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzofuran-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran-3-carboxylic acid methyl ester(4687-24-5)
• EPA Substance Registry System: Benzofuran-3-carboxylic acid methyl ester(4687-24-5)

Safety Data

• Hazardous Substances Data: 4687-24-5(Hazardous Substances Data)

Usage

General Description

Benzofuran-3-carboxylic acid methyl ester is a chemical compound that belongs to the class of benzofuran derivatives. It is commonly used in the synthesis of various pharmaceutical and agrochemical products. Benzofuran-3-carboxylic acid methyl ester has been studied for its potential biological activities, including antitumor, antiviral, and anti-inflammatory properties. Benzofuran-3-carboxylic acid methyl ester is also used as a building block in the synthesis of organic molecules and is an important intermediate in the pharmaceutical industry. It is important to handle and use this compound with care, as it may have potential hazards if not properly managed.

Upstream product

• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 149-73-5 trimethyl orthoformate 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 174211-74-6 benzo[b]furan-3-yl trifluoromethane sulfonate 
• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 
• 7169-17-7 2-diazo-1-(2-methoxyphenyl)ethanone 
• 579-75-9 2-Methoxybenzoic acid 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 39891-56-0 (rac)-methyl 2,3-dihydrobenzo[b]furan-3-carboxylate 
• 3375-31-3 palladium diacetate 
• 174180-55-3 3-(2-Bromo-phenoxy) acrylic acid methyl ester 
• 60-29-7 diethyl ether 
• 1103768-13-3 2-(2-bromophenyl)-3-oxo-propionic acid methyl ester 

Downstream Products

• 26537-68-8 benzofurane-3-carboxylic acid 
• 4687-23-4 3-hydroxymethylbenzofuran 
• 165735-63-7 benzofuran-3-ylmethanamine 

Relevant articles and documents

Palladium-Catalyzed, Copper(I)-Promoted Methoxycarbonylation of Arylboronic Acids with O-Methyl S-Aryl Thiocarbonates

Here, we report O-methyl S-aryl thiocarbonates as a versatile esterification reagent for palladium-catalyzed methoxycarbonylation of arylboronic acid in the presence of copper(I) thiophene-2-carboxylate (CuTC). The reaction condition is mild, and a variety of substituents including sensitive-Cl,-Br, and free-NH2 could be tolerated. Further applications in the late-stage esterification of some pharmaceutical drugs demonstrate the broad utility of this method.

Palladium-catalyzed oxidative cyclization of 3-phenoxyacrylates: An approach to construct substituted benzofurans from phenols

In this paper, a novel and applicable synthesis of benzofurans from commercially available phenols and propiolate through the direct oxidative cyclization has been developed. In the presence of Pd(OAc)2/PPh 3 and CF3COsub

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