26537-68-8Relevant articles and documents
-
Reichstein,Baud
, p. 892 (1937)
-
A benzofuran -3 - carboxylic acid (by machine translation)
-
Paragraph 0009; 0015; 0016; 0018; 0020; 0022; 0024, (2018/07/30)
The invention relates to a benzofuran - 3 - carboxylic acid preparation method, the method using the intermediate 1 as raw materials, under alkaline conditions in the open-loop, the closed-loop process for preparing benzofuran - 3 - carboxylic acid. The method is characterized in that the mild reaction conditions, the operation is simple, high yield, is suitable for industrial production. (by machine translation)
Silver-catalyzed protodecarboxylation of heteroaromatic carboxylic acids
Lu, Pengfel,Sanchez, Carolina,Cornella, Josep,Larrosa, Igor
supporting information; experimental part, p. 5710 - 5713 (2010/02/28)
[Chemical Equation Presented] A simple and highly efficient protodecarboxylation procedure for a variety of heteroaromatic carboxylic acids catalyzed by Ag2CO3 and AcOH in DMSO is described. This methodology can also perform the selective monoprotodecarboxylation of several aromatic dicarboxylic acids.
Novel indol carboxylic acid bispyridyl carboxamide derivatives as 5-HT2c receptor antagonists
-
Page/Page column 12, (2009/10/21)
Disclosed herein are a new indole carboxylic acid bispyridyl carboxamide derivative, a preparation method thereof, and a composition for prevention or treatment of obesity, urinary disorders, and CNS disorders, containing the same as an active ingredient. Because the indole carboxylic acid bispyridyl carboxamide derivatives according to the present invention have high affinity for 5-HT2c receptors, act selectively on the 5-HT2c receptors, the derivatives rarely have adverse effects caused by other receptors. Because the derivatives effectively inhibit serotonin activity, they may be useful for treatment or prevention of obesity; urinary disorders such as urinary incontinence, premature ejaculation, erectile dysfunction, and prostatic hyperplasia; CNS disorders such as depression, anxiety, concern, panic disorder, epilepsy, obsessive-compulsive disorder, migraine, sleep disorder, withdrawal from drug abuse, Alzheimer's disease, and schizophrenia, associated with 5-HT2c receptors.