52489-34-6

Basic information

• Product Name: 3-Benzofurancarboxylic acid, 2-ethyl-
• Synonyms: 2-Aethyl-cumaron-carbonsaeure-(3);2-Aethyl-benzofuran-3-carbonsaeure;2-Ethyl-benzofuran-3-carboxylic acid;2-Aethyl-benzofuran-carbonsaeure-(3)
• CAS NO: 52489-34-6
• Molecular Formula: C11H10O3
• Molecular Weight: 190.199
• Mol File: 52489-34-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 118 °C
• CAS DataBase Reference: 3-Benzofurancarboxylic acid, 2-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzofurancarboxylic acid, 2-ethyl-(52489-34-6)
• EPA Substance Registry System: 3-Benzofurancarboxylic acid, 2-ethyl-(52489-34-6)

Safety Data

• Hazardous Substances Data: 52489-34-6(Hazardous Substances Data)

Upstream product

• 5963-77-9 pent-2-ynoic acid 
• 5661-50-7 N-(phenoxy)acetamide 
• 90-02-8 salicylaldehyde 
• 1646-26-0 1-(benzo[b]furan-2-yl)ethanone 
• 3131-63-3 2-ethylbenzofuran 
• 26537-68-8 benzofurane-3-carboxylic acid 
• 75-03-6 ethyl iodide 
• 40800-82-6 3-propionyl-3H-benzofuran-2-one 
• 4265-18-3 3-acetyl-2-ethylbenzofuran 

Relevant articles and documents

Construction of Benzofuran-3(2 H)-one Scaffolds with a Quaternary Center via Rh/Co Relay Catalyzed C-H Functionalization/Annulation of N-Aryloxyacetamides and Propiolic Acids

An unprecedented synthesis of valuable benzofuran-3(2H)-one scaffolds with a quaternary center was developed via Rh/Co relay catalyzed C-H functionalization/annulation of N-aryloxyacetamides with propiolic acids in moderate to good yields. The reaction features the simultaneous construction of the benzofuran motif containing a C2 quaternary center and a C3 carbonyl group. The preliminary mechanism study verified that the O atom of C3 carbonyl group originates from molecular oxygen.

METHODS FOR THE HOMOLOGATION OF BENZOFURANCARBOXYLIC ACIDS USING DIANIONIC INTERMEDIATES

Dianions (2), (5), and (10), can be derived from the corresponding benzofurancarboxylic acids using lithium diisopropylamide, and are useful intermediates for the homologation of the parent acids.