4695-62-9 Usage
Description
(-)-FENCHONE, also known as d-Fenchone, is a colorless, oily liquid with a camphor-like odor that is powerful, sweet, and has a warm, somewhat bitter, and burning taste. It is found in various essential oils, such as those from Thuja plicata, Thuja occidentalis, Thuja standishii, Russian anise, fennel, and a few Artemisia varieties, with the highest levels found in fennel oil (12 to 19%). It is also reported to be found in basil, caraway, cedar leaf oil, cloves, dill, licorice, and thyme. (-)-FENCHONE is produced and qualified by HWI Pharma Services GmbH, and its exact content can be determined by quantitative NMR.
Uses
1. Used in the Analysis of Herbal Medicinal Products:
(-)-FENCHONE is used as a reference standard in the analysis of herbal medicinal products, aiding in the identification and quantification of various components in these products.
2. Used as Flavor in Foods:
(-)-FENCHONE is used as a flavoring agent in the food industry due to its cooling camphoreous taste with green citrus lime nuances. It adds a unique and pleasant flavor to various food products.
3. Used in Perfumes:
(-)-FENCHONE is utilized in the perfume industry for its powerful and sweet camphor-like odor, contributing to the overall scent profile of various fragrances.
4. Used in the Flavor and Fragrance Industry:
(-)-FENCHONE is used as a key component in the creation of flavors and fragrances, capitalizing on its distinct aroma characteristics and taste threshold values. In the flavor industry, it is used to enhance the taste of various products, while in the fragrance industry, it contributes to the overall scent profile of perfumes and other scented products.
5. Used in Essential Oils:
(-)-FENCHONE is found in several essential oils, such as those from Thuja species, Russian anise, fennel, and Artemisia varieties. It is used to enhance the aroma and therapeutic properties of these essential oils, which are widely used in aromatherapy, massage, and other applications.
Preparation
Isolated from cedarleaf oil (thuja oil).
Purification Methods
The oily liquid is purified by distillation in a vacuum and is very soluble in EtOH and Et2O. [Boyle et al. J Chem Soc, Chem Commun 395 1971, Hückel Justus Liebigs Ann Chem 549 186 1941, (±)-isomer: Braun & Jacob Chem Ber 66 1461 1933.] It forms two oximes, cis-oxime: m 167o (crystallises from pet ether) [] D +46.5o (c 2, EtOH), O-benzoyloxime m 81o, [] D +49o
Check Digit Verification of cas no
The CAS Registry Mumber 4695-62-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,9 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4695-62:
(6*4)+(5*6)+(4*9)+(3*5)+(2*6)+(1*2)=119
119 % 10 = 9
So 4695-62-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H16O/c1-9(2)7-4-5-10(3,6-7)8(9)11/h7H,4-6H2,1-3H3/t7-,10+/m1/s1
4695-62-9Relevant articles and documents
Synthesis of Terpineol from Alpha-Pinene Catalyzed by α-Hydroxy Acids
Hu, Yi-Ming,Huang, Xiao-Rui,Meng, Zhong-Lei,Qin, Rong-Xiu,Wen, Ru-Si,Zhou, Yong-Hong
, (2022/02/17)
We report the use of five alpha-hydroxy acids (citric, tartaric, mandelic, lactic and glycolic acids) as catalysts in the synthesis of terpineol from alpha-pinene. The study found that the hydration rate of pinene was slow when only catalyzed by alpha-hydroxyl acids. Ternary composite catalysts, composed of AHAs, phosphoric acid, and acetic acid, had a good catalytic performance. The reaction step was hydrolysis of the intermediate terpinyl acetate, which yielded terpineol. The optimal reaction conditions were as follows: alpha-pinene, acetic acid, water, citric acid, and phosphoric acid, at a mass ratio of 1:2.5:1:(0.1–0.05):0.05, a reaction temperature of 70? C, and a reaction time of 12–15 h. The conversion of alpha-pinene was 96%, the content of alpha-terpineol was 46.9%, and the selectivity of alpha-terpineol was 48.1%. In addition, the catalytic performance of monolayer graphene oxide and its composite catalyst with citric acid was studied, with acetic acid used as an additive.
Secondary Phosphine Oxides as Multitalented Preligands En Route to the Chemoselective Palladium-Catalyzed Oxidation of Alcohols
Vasseur, Alexandre,Membrat, Romain,Gatineau, David,Tenaglia, Alphonse,Nuel, Didier,Giordano, Laurent
, p. 728 - 732 (2017/03/13)
Secondary phosphine oxides O=PHR2 (SPOs) were identified as multitalented preligands for the chemoselective Pd-catalyzed oxidation of alcohols by a hydrogen-abstracting methodology. SPOs were found to promote the hydrogen-abstraction step as well as hydrogen transfer to a Michael acceptor by generating a putative active H?Pd species. The catalytic system operates under neutral conditions and was proven to be compatible with various electrophilic and nucleophilic functionalities within the substrates as well as water- and air-sensitive functional groups.
