469886-49-5

Basic information

• Product Name: (4S)-2-(2-benzyloxycarbonylethyl)-4-(tert-butyldiphenylsilyloxymethyl)-2-methyloxazolidine-3-carboxylic acid tert-butyl ester
• Synonyms: (4S)-2-(2-benzyloxycarbonylethyl)-4-(tert-butyldiphenylsilyloxymethyl)-2-methyloxazolidine-3-carboxylic acid tert-butyl ester
• CAS NO: 469886-49-5
• Molecular Weight: 617.858
• Mol File: 469886-49-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S)-2-(2-benzyloxycarbonylethyl)-4-(tert-butyldiphenylsilyloxymethyl)-2-methyloxazolidine-3-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-2-(2-benzyloxycarbonylethyl)-4-(tert-butyldiphenylsilyloxymethyl)-2-methyloxazolidine-3-carboxylic acid tert-butyl ester(469886-49-5)
• EPA Substance Registry System: (4S)-2-(2-benzyloxycarbonylethyl)-4-(tert-butyldiphenylsilyloxymethyl)-2-methyloxazolidine-3-carboxylic acid tert-butyl ester(469886-49-5)

Safety Data

• Hazardous Substances Data: 469886-49-5(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 123-76-2 levulinic acid 
• 6939-75-9 benzyl levulinate 
• 469886-48-4 (2S)-[1-(tert-butyldiphenylsilanyloxymethyl)-2-hydroxyethyl]carbamic acid tert-butyl ester 

Downstream Products

• 469886-61-1 (R)-4-((2S,3R)-1-Benzyl-4-oxo-3-phenoxy-azetidin-2-yl)-2-(2-benzyloxycarbonyl-ethyl)-2-methyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 469886-51-9 (4S)-2-(2-benzyloxycarbonylethyl)-4-formyl-2-methyloxazolidine-3-carboxylic acid tert-butyl ester 
• 469886-50-8 (4R)-2-(2-benzyloxycarbonylethyl)-4-hydroxymethyl-2-methyloxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis of a polymer-supported oxazolidine aldehyde for asymmetric chemistry

An expedient synthesis of the polymer-supported aldehyde 3, as a Garner aldehyde equivalent, is described. Oxazolidine 3 may be obtained through preformation of aldehyde linker 4 in solution and loaded onto amine-terminating resin under peptide-coupling conditions, or alternatively via oxidation of polymer-bound alcohol 14. The integrity of the serine-derived stereocenter is maintained through all steps of the synthesis.