471938-27-9

Basic information

• Product Name: methyl 1-(4-aminophenyl)piperidine-4-carboxylate
• Synonyms: methyl 1-(4-aminophenyl)piperidine-4-carboxylate
• CAS NO: 471938-27-9
• Molecular Weight: 234.298
• Mol File: 471938-27-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 1-(4-aminophenyl)piperidine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-(4-aminophenyl)piperidine-4-carboxylate(471938-27-9)
• EPA Substance Registry System: methyl 1-(4-aminophenyl)piperidine-4-carboxylate(471938-27-9)

Safety Data

• Hazardous Substances Data: 471938-27-9(Hazardous Substances Data)

Upstream product

• 7595-60-0 methyl 1-(4-nitrophenyl)piperidine-4-carboxylate 
• 350-46-9 4-Fluoronitrobenzene 
• 2971-79-1 isonipecotic acid methyl ester 

Downstream Products

• 1085839-59-3 1-{4-[(2-phenyl-5-trifluoromethyl-oxazole-4-carbonyl)-amino]-phenyl}-piperidine-4-carboxylic acid methyl ester 
• 1085839-92-4 1-(1-{4-[(2-phenyl-5-trifluoromethyl-oxazole-4-carbonyl)-amino]-phenyl}-piperidine-4-carbonyl)-piperidine-4-carboxylic acid ethyl ester 
• 1085839-61-7 1-{4-[(2-phenyl-5-trifluoromethyl-oxazole-4-carbonyl)-amino]-phenyl}-piperidine-4-carboxylic acid 
• 471937-86-7 [1-(4-aminophenyl)piperidin-4-yl]methanol 

Relevant articles and documents

Porphyrin Donor and Tunable Push–Pull Acceptor Conjugates—Experimental Investigation of Marcus Theory

We report on a series of electron donor–acceptor conjugates incorporating a ZnII–porphyrin-based electron donor and a variety of non-conjugated rigid linkers connecting to push–pull chromophores as electron acceptors. The electron acceptors comprize multicyanobutadienes or extended tetracyanoquinodimethane analogues with first reduction potentials ranging from ?1.67 to ?0.23 V vs. Fc+/Fc in CH2Cl2, which are accessible through a final-step cycloaddition–retroelectrocyclization (CA-RE) reaction. Characterization of the conjugates includes electrochemistry, spectroelectrochemistry, DFT calculations, and photophysical measurements in a range of solvents. The collected data allows for the construction of multiple Marcus curves that consider electron-acceptor strength, linker length, and solvent, with data points extending well into the inverted region. The enhancement of electron–vibration couplings, resulting from the rigid spacers and, in particular, multicyano-groups in the conformationally highly fixed push–pull acceptor chromophores affects the charge-recombination kinetics in the inverted region drastically.

DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS

Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.