7595-60-0

Basic information

• Product Name: METHYL 1-(4-NITROPHENYL)-4-PIPERIDINECARBOXYLATE
• Synonyms: methyl 1-(4-nitrophenyl)piperidine-4-carboxylate;METHYL 1-(4-NITROPHENYL)-4-PIPERIDINECARBOXYLATE
• CAS NO: 7595-60-0
• Molecular Formula: C₁₃H₁₆N₂O₄
• Molecular Weight: 264.28
• Mol File: 7595-60-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 133-135°C
• Boiling Point: 415.9°Cat760mmHg
• Flash Point: 205.3°C
• Appearance: /
• Density: 1.251g/cm³
• Vapor Pressure: 3.98E-07mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: METHYL 1-(4-NITROPHENYL)-4-PIPERIDINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 1-(4-NITROPHENYL)-4-PIPERIDINECARBOXYLATE(7595-60-0)
• EPA Substance Registry System: METHYL 1-(4-NITROPHENYL)-4-PIPERIDINECARBOXYLATE(7595-60-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 7595-60-0(Hazardous Substances Data)

Usage

General Description

Methyl 1-(4-nitrophenyl)-4-piperidinecarboxylate is a chemical compound with the molecular formula C15H19NO4. It is a piperidine derivative with a methyl ester group and a nitrophenyl group attached to the piperidine ring. METHYL 1-(4-NITROPHENYL)-4-PIPERIDINECARBOXYLATE is commonly used in pharmaceutical research and drug development, particularly in the synthesis of potential drug candidates. It has been studied for its potential pharmacological properties, including its role as a potential analgesic and its inhibitory effects on certain neurotransmitters. The compound's unique structure and properties make it a valuable tool for medicinal chemistry and pharmacological studies.

InChI:InChI=1/C13H16N2O4/c1-19-13(16)10-6-8-14(9-7-10)11-2-4-12(5-3-11)15(17)18/h2-5,10H,6-9H2,1H3

Upstream product

• 2971-79-1 isonipecotic acid methyl ester 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 471938-27-9 methyl 1-(4-aminophenyl)piperidine-4-carboxylate 
• 1445868-97-2 5-[1-(4-[(E)-1-(5-nitro-2-furyl)methylidene]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445868-98-3 3-methyl-5-[1-(4-[(E)-1-(5-nitro-2-furyl)methylidene]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445868-99-4 3-ethyl-5-[1-(4-[(E)-1-(5-nitro-2-furyl)methylidene]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445869-00-0 3-benzyl-5-[1-(4-[(E)-1-(5-nitro-2-furyl)methylidene]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445869-05-5 5-[1-(4-[(5-nitro-2-furyl)methyl]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445869-06-6 3-methyl-5-[1-(4-[(5-nitro-2-furyl)methyl]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445868-89-2 N-4-[4-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)piperidino]phenyl-5-nitro-2-furamide 
• 1445869-07-7 3-ethyl-5-[1-(4-[(5-nitro-2-furyl)methyl]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445869-08-8 3-benzyl-5-[1-(4-[(5-nitro-2-furyl)methyl]aminophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445868-90-5 N-4-[4-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)piperidino]phenyl-5-nitro-2-furamide 
• 1445869-21-5 1-(4-nitrophenyl)-4-piperidinecarbohydrazide 
• 1445869-22-6 5-[1-(4-nitrophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 
• 1445869-24-8 3-methyl-5-[1-(4-nitrophenyl)-4-piperidyl]-2,3-dihydro-1,3,4-oxadiazol-2-one 

Relevant articles and documents

Porphyrin Donor and Tunable Push–Pull Acceptor Conjugates—Experimental Investigation of Marcus Theory

We report on a series of electron donor–acceptor conjugates incorporating a ZnII–porphyrin-based electron donor and a variety of non-conjugated rigid linkers connecting to push–pull chromophores as electron acceptors. The electron acceptors comprize multicyanobutadienes or extended tetracyanoquinodimethane analogues with first reduction potentials ranging from ?1.67 to ?0.23 V vs. Fc+/Fc in CH2Cl2, which are accessible through a final-step cycloaddition–retroelectrocyclization (CA-RE) reaction. Characterization of the conjugates includes electrochemistry, spectroelectrochemistry, DFT calculations, and photophysical measurements in a range of solvents. The collected data allows for the construction of multiple Marcus curves that consider electron-acceptor strength, linker length, and solvent, with data points extending well into the inverted region. The enhancement of electron–vibration couplings, resulting from the rigid spacers and, in particular, multicyano-groups in the conformationally highly fixed push–pull acceptor chromophores affects the charge-recombination kinetics in the inverted region drastically.

Nitrofurfuryl Substituted Phenyl Linked Piperidino-Oxadiazoline Conjugates As Anti-Tubercular Agents And Process For The Preparation Thereof

The present invention provides nitrofurfuryl substituted phenyl linked piperidino-oxadiazolone compounds of general formula (A) as anti-tubercular agents; wherein G=formula (B); X═H, F; R═H, CH3, C2H5, Benzyl.

NITROFURFURYL SUBSTITUTED PHENYL LINKED PIPERIDINO-OXADIAZOLINE CONJUGATES AS ANTI-TUBERCULAR AGENTS AND PROCESS FOR THE PREPARATION THEREOF

The present invention provides nitrofurfuryl substituted phenyl linked piperidino-oxadiazolone compounds of general formula (A) as anti-tubercular agents; wherein G= formula (B); X=H, F; R=H, CH3, C2H5, Benzyl.