473416-33-0 Usage
Description
(5-Fluorobenzofuran-2-yl)boronic acid is an organic compound that features a boron atom bonded to a benzofuran ring with a fluorine atom at the 5-position. This unique structure endows it with specific chemical properties, making it a valuable intermediate in the synthesis of various heterocyclic compounds.
Uses
Used in Pharmaceutical Industry:
(5-Fluorobenzofuran-2-yl)boronic acid is used as a reagent for the preparation of heterocyclic compounds that can inhibit the activity of PASK (Proline-Alanine-Serine-Proline Kinase). This inhibition is particularly useful for the treatment of diseases like diabetes mellitus, as it can help regulate cellular processes and improve overall metabolic health. By targeting PASK, these heterocyclic compounds have the potential to offer novel therapeutic approaches for managing diabetes and its associated complications.
Check Digit Verification of cas no
The CAS Registry Mumber 473416-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,3,4,1 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 473416-33:
(8*4)+(7*7)+(6*3)+(5*4)+(4*1)+(3*6)+(2*3)+(1*3)=150
150 % 10 = 0
So 473416-33-0 is a valid CAS Registry Number.
473416-33-0Relevant articles and documents
HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK
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Page/Page column 66, (2012/09/21)
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.
NOVEL 1H-INDAZOLE COMPOUND
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Page 67, (2008/06/13)
The present invention provides a novel 1H-indazole compound having an excellent JNK inhibitory action. More specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. Wherein R1 is a C6-C14 aromatic cyclic hydrocarbon group etc.; R2, R4 and R5 each independently represent a hydrogen atom, a halogen atom, a cyano group etc.; L is a single bond, or a C1-C6 alkylene group etc.; X is a single bond, or a group represented by -CO-NH- or -NH-CO-, etc.; and Y is a C3-C8 cycloalkyl group, a C6-C14 aromatic cyclic hydrocarbon group or a 5- to 14-membered aromatic heterocyclic group etc.
