476429-18-2

Basic information

• Product Name: methyl 2-methyl-2-(4-(trifluoromethyl)phenyl)propanoate
• Synonyms: methyl 2-methyl-2-(4-(trifluoromethyl)phenyl)propanoate
• CAS NO: 476429-18-2
• Molecular Weight: 246.229
• Mol File: 476429-18-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: methyl 2-methyl-2-(4-(trifluoromethyl)phenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-methyl-2-(4-(trifluoromethyl)phenyl)propanoate(476429-18-2)
• EPA Substance Registry System: methyl 2-methyl-2-(4-(trifluoromethyl)phenyl)propanoate(476429-18-2)

Safety Data

• Hazardous Substances Data: 476429-18-2(Hazardous Substances Data)

Upstream product

• 547-63-7 Methyl isobutyrate 
• 455-13-0 4-Iodobenzotrifluoride 
• 32857-62-8 4-Trifluoromethylphenylacetic acid 
• 135325-18-7 methyl 2-(4-(trifluoromethyl)phenyl)acetate 
• 74-88-4 methyl iodide 
• 98-56-6 4-chlorobenzotrifluoride 
• 721-63-1 (4-trifluoromethylphenyl)acetic acid ethyl ester 
• 31469-15-5 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene 
• 402-43-7 p-trifluoromethylphenyl bromide 

Downstream Products

• 32445-89-9 2-methyl-2-(4-(trifluoromethyl)phenyl)propanoic acid 
• 1040860-53-4 C₁₁H₁₀ClF₃O 
• 1035260-99-1 diethyl 2-(2-methyl-2-(4-(trifluoromethyl)phenyl)propanoyl)malonate 

Relevant articles and documents

ARYL-SUBSTITUTED ACETAMIDE AND PYRROLIDIN-2-ONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SEIZURES

Aryl-substituted acetamide and pyrrolidin-2-one (γ-butyrolactam) derivatives have useful activity in the inhibition, prevention, or treatment of seizures. The derivatives may be useful in the treatment of epilepsy, including medically refractory epilepsy, and nerve agent poisoning.

Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: Synthesis of chiral benzofuranones

Pd(II)-catalyzed enantioselective C-H activation of phenylacetic acids followed by an intramolecular C-O bond formation afforded chiral benzofuranones. This reaction provides the first example of enantioselecctive C-H functionalizations through Pd(II)/Pd(IV) redox catalysis.

Arylation of esters catalyzed by the Pd(I) dimer {[P(t-Bu)]PdBr}

Conditions for the coupling of bromoarenes with esters using a single base and catalyst with improved turnover numbers are described. These general conditions were made possible by using the Pd(l) catalyst {[P(f-Bu) 3]PdBr}2. Reactions of acetates, propionates, and isobutyrates are presented, and reactions of all three classes of esters on a 10 g scale are described.