478646-28-5

Basic information

• Product Name: (R)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL
• Synonyms: (R)-Benzyl 1,5-dihydroxypentan-2-ylcarbamate;(R)-2-N-Cbz-aminopentane-1,5-diol;(R)-(4-Hydroxy-1-hydroxymethylbutyl)carbamic acid benzyl ester;REF DUPL: (R)-2-N-Cbz-amino-pentane-1,5-diol;REF DUPL: (S)-benzyl 1,5-dihydroxypentan-2-ylcarbamate;Carbamic acid, [(1R)-4-hydroxy-1-(hydroxymethyl)butyl]-, phenylmethyl ester (9CI)
• CAS NO: 478646-28-5
• Molecular Formula: C₁₃H₁₉NO₄
• Molecular Weight: 253.29
• Mol File: 478646-28-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 485.2 °C at 760 mmHg
• Flash Point: 247.2 °C
• Appearance: /
• Density: 1.192g/cm³
• Vapor Pressure: 3.17E-10mmHg at 25°C
• Refractive Index: 1.546
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL(478646-28-5)
• EPA Substance Registry System: (R)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL(478646-28-5)

Safety Data

• Hazardous Substances Data: 478646-28-5(Hazardous Substances Data)

Usage

General Description

"(R)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL" is a chemical compound that belongs to the class of amino alcohols. It is characterized by the presence of an N-CBZ (carboxybenzyl) group and an amino group on a pentane-1,5-diol backbone. (R)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL is commonly used as a building block in organic synthesis and medicinal chemistry. It is often employed in the preparation of various pharmaceuticals and bioactive molecules due to its versatile reactivity and functional groups. Additionally, it has potential applications in drug design and development, as well as in the production of complex organic molecules for medicinal purposes.

InChI:InChI=1/C13H19NO4/c15-8-4-7-12(9-16)14-13(17)18-10-11-5-2-1-3-6-11/h1-3,5-6,12,15-16H,4,7-10H2,(H,14,17)/t12-/m1/s1

Upstream product

• 6893-26-1 D-Glutamic acid 
• 16422-27-8 1,5-dimethyl (2R)-2-aminopentanedioate 
• 67436-17-3 benzyloxycarbonylglutamic acid dimethyl ester 

Downstream Products

• 1609164-89-7 6-chloro-8-[(2,6-difluorobenzyl)oxy]-N-[(2R)-1,5-dihydroxypentan-2-yl]-2-methylimidazo[1,2-a]-pyridine-3-carboxamide 
• 1384476-38-3 (R)-4-(benzyloxycarbonylamino)-5-hydroxypentyl acetate 
• 1384476-39-4 (R)-2-(benzyloxycarbonylamino)-5-hydroxypentyl acetate 
• 1384476-40-7 (R)-2-(benzyloxycarbonylamino)pentane-1,5-diyl diacetate 
• 397246-12-7 tert-butyl N-[(2R)-1,5-dihydroxypentan-2-yl]carbamate 
• 1384476-05-4 (R)-5-hydroxy-4-(2-nitrophenylsulfonamido)pentyl acetate 
• 1384476-07-6 (R)-2-(2-nitrophenylsulfonamido)pentane-1,5-diyl diacetate 
• 1384476-06-5 (R)-5-hydroxy-2-(2-nitrophenylsulfonamido)pentyl acetate 
• 1384476-41-8 (R)-5-hydroxy-4-(4-methylphenylsulfonamido)pentyl acetate 
• 1384476-42-9 (R)-5-hydroxy-2-(4-methylphenylsulfonamido)pentyl acetate 
• 1384476-43-0 (R)-2-(4-methylphenylsulfonamido)pentane-1,5-diyl diacetate 
• 1384476-04-3 (R)-N-(1,5-dihydroxypentan-2-yl)-2-nitrobenzenesulfonamide 

Relevant articles and documents

A kind of optical active pharmaceutical process for the preparation of intermediates

The invention relates to a preparation method of an optical active compound, represented by formula I, or a hydrochloride of the optical active compound by taking a compound with optical activity as a starting material. Raw materials of the preparation method are cheap and easily available; no splitting is needed; the whole technological operation is simple and convenient; cost is low; pollution on environment is less; and the preparation method is suitable for industrialized production. In the formula I, n is 1 or 2 or 3.