479-30-1 Usage
Description
3,4-Pyridinedicarboxylic acid, 5-hydroxy-6-methylis a chemical compound with the molecular formula C7H7NO4. It is characterized by the presence of a pyridine ring with two carboxylic acid groups at the 3rd and 4th positions, a hydroxyl group at the 5th position, and a methyl group at the 6th position. 3,4-Pyridinedicarboxylic acid, 5-hydroxy-6-methylis known for its potential applications in various fields, particularly in biological and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
3,4-Pyridinedicarboxylic acid, 5-hydroxy-6-methylis used as a research compound for identifying the 4-pyridoxic acid dehydrogenase gene in pyridoxine catabolism of Mesorhizobium loti MAFF303099. This application is significant in understanding the metabolic pathways and enzyme functions related to pyridoxine (vitamin B6), which plays a crucial role in various cellular processes, including the synthesis of neurotransmitters, amino acids, and lipids.
Used in Chemical Synthesis:
3,4-Pyridinedicarboxylic acid, 5-hydroxy-6-methylcan also be used as a building block or intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structural features make it a valuable component in the development of novel compounds with specific biological activities or improved properties.
Used in Analytical Chemistry:
3,4-Pyridinedicarboxylic acid, 5-hydroxy-6-methylcan be employed as a reference material or standard in analytical chemistry, particularly in the development and validation of analytical methods for the determination of similar compounds in complex matrices. Its distinct chemical and physical properties can be utilized to optimize and improve the selectivity, sensitivity, and accuracy of analytical techniques, such as chromatography, mass spectrometry, and spectrophotometry.
Check Digit Verification of cas no
The CAS Registry Mumber 479-30-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 479-30:
(5*4)+(4*7)+(3*9)+(2*3)+(1*0)=81
81 % 10 = 1
So 479-30-1 is a valid CAS Registry Number.
479-30-1Relevant articles and documents
PLP catabolism: Identification of the 4-pyridoxic acid dehydrogenase gene in Mesorhizobium loti MAFF303099
Mukherjee, Tathagata,Kinsland, Cynthia,Begley, Tadhg P.
, p. 458 - 464 (2007)
The function of the mlr6793 gene from Mesorhizobium loti MAFF303099 has been identified. This gene encodes 4-pyridoxic acid dehydrogenase, an enzyme involved in the catabolism of PLP (Vitamin B6). This enzyme was overexpressed in Escherichia coli and characterized. 4-Pyridoxic acid dehydrogenase is a 33 kDa protein that catalyzes the four electron oxidation of 4-pyridoxic acid to 3-hydroxy-2-methylpyridine-4,5-dicarboxylate, using nicotinamide adenine dinucleotide as a cofactor. The kcat for NADH production is 0.01 s-1. The KM values for 4-pyridoxic acid and NAD are 5.8 and 6.6 μM, respectively.
