4805-28-1

Basic information

• Product Name: 1-benzoyl-5-benzyl-2-(4-chlorophenyl)-5-azaspiro[2.4]heptane-6,7-dione
• Synonyms: 1-benzoyl-5-benzyl-2-(4-chlorophenyl)-5-azaspiro[2.4]heptane-6,7-dione
• CAS NO: 4805-28-1
• Molecular Weight: 311.768
• Mol File: 4805-28-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-benzoyl-5-benzyl-2-(4-chlorophenyl)-5-azaspiro[2.4]heptane-6,7-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzoyl-5-benzyl-2-(4-chlorophenyl)-5-azaspiro[2.4]heptane-6,7-dione(4805-28-1)
• EPA Substance Registry System: 1-benzoyl-5-benzyl-2-(4-chlorophenyl)-5-azaspiro[2.4]heptane-6,7-dione(4805-28-1)

Safety Data

• Hazardous Substances Data: 4805-28-1(Hazardous Substances Data)

Upstream product

• 5336-41-4 methyl 1-benzyl-4,5-dioxopyrrolidine-3-carboxylate 
• 104-88-1 4-chlorobenzaldehyde 
• 23583-21-3 ethyl-3-benzylamino propionate 
• 100-46-9 benzylamine 
• 5336-50-5 1-benzyl-4,5-dioxopyrrolidine-3-carboxylic acid ethyl ester 

Relevant articles and documents

NHC-catalyzed [4 + 2] annulations of allenoates and 2,3-dioxopyrrolidine derivatives

A facile NHC-catalyzed [2 + 4] annulation of allenoates with 2,3-dioxypyrrolidine derivatives was discovered, which paved a new avenue for the construction of highly substituted pyranopyrrole with moderate to good yields, high atom economy and mild reaction conditions. This journal is

Au(I)/(R)-BINOL-Ti(IV) concerted catalyzed asymmetric cascade cycloaddition reaction of arylalkynols

An efficient catalytic asymmetric cascade cycloaddition reaction of arylalkynols with dioxopyrrolidines was developed. This reaction was achieved using Au(I) and (R)-BINOL-Ti(IV) bimetallic catalysts and exclusively delivered a series of chiral oxo-bridged bicyclic benzooxacine compounds in up to 86% yield with 96% ee as well as >33:1 dr. Meanwhile, three new σ bonds and three new stereogenic centers were formed in a one-pot process.