481-25-4

Basic information

• Product Name: 4-methylcholest-7-en-3-ol
• Synonyms: 4-methylcholest-7-en-3-ol;4α-Methyl-5α-cholest-7-en-3β-ol;Δ7-Methostenol
• CAS NO: 481-25-4
• Molecular Formula: C28H48O
• Molecular Weight: 400.68
• Mol File: 481-25-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 487.5°C at 760 mmHg
• Flash Point: 213.7°C
• Appearance: /
• Density: 0.98g/cm³
• Vapor Pressure: 1.51E-11mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: 4-methylcholest-7-en-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylcholest-7-en-3-ol(481-25-4)
• EPA Substance Registry System: 4-methylcholest-7-en-3-ol(481-25-4)

Safety Data

• Hazardous Substances Data: 481-25-4(Hazardous Substances Data)

Usage

Description

4-methylcholest-7-en-3-ol, also known as Methost-7-enol, is a naturally occurring steroidal compound derived from the cholesterol family. It is characterized by the presence of a methyl group at the 4th carbon and a double bond at the 7th carbon, with a hydroxyl group at the 3rd carbon. 4-methylcholest-7-en-3-ol exhibits significant biological activities and has been the subject of research for its potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
4-methylcholest-7-en-3-ol is used as a bioactive compound for its potent inhibitory activity against various human cancer cell lines. It has demonstrated effectiveness against liver cancer, nasopharyngeal, and colon cancer cells, making it a promising candidate for the development of novel anticancer drugs.
In addition to its direct anticancer properties, 4-methylcholest-7-en-3-ol may also be utilized in the development of drug delivery systems to enhance the bioavailability and therapeutic outcomes of other cancer-fighting agents. Its unique structural features could potentially be exploited to improve the targeting and efficacy of cancer treatments.
Furthermore, given its steroidal nature, 4-methylcholest-7-en-3-ol may also find applications in the synthesis of other pharmaceutical compounds, including hormones and other therapeutic agents. Its ability to modulate cellular signaling pathways and interact with various biological targets could make it a versatile building block in the development of new drugs for a range of medical conditions.

InChI:InChI=1/C28H48O/c1-18(2)8-7-9-19(3)22-12-13-24-21-10-11-23-20(4)26(29)15-17-28(23,6)25(21)14-16-27(22,24)5/h10,18-20,22-26,29H,7-9,11-17H2,1-6H3/t19-,20+,22-,23+,24+,25+,26+,27-,28+/m1/s1

Upstream product

• 2789-43-7 4α-methyl-5α-cholest-7-en-3-one 
• 83-46-5 β-sitosterol 
• 57-88-5 cholesterol 
• 313-04-2 demosterol 
• 2364-32-1 3β-acetoxy-4α-methyl-5α-cholest-7-en-24-one 
• 15459-85-5 5α-cholest-7-en-3-one 
• 19753-67-4 3-methyl-1-(triphenylphosphoranyliden)-2-butanone 
• 63109-20-6 Acetic acid (3S,4S,5S,9R,10S,13R,14R,17R)-4,10,13-trimethyl-17-((S)-1-methyl-2-oxo-ethyl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 63109-21-7 Acetic acid (3S,4S,5S,9R,10S,13R,14R,17R)-17-((E)-(R)-1,5-dimethyl-4-oxo-hex-2-enyl)-4,10,13-trimethyl-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 

Downstream Products

• 109097-94-1 3β-benzoyloxy-4α-methyl-5α-cholest-7-ene 
• 62014-96-4 4α-methyl-5α-cholest-8(14)-en-3β-ol 

Relevant articles and documents

Novel nuclear methylation of sterols by the nematode Caenorhabditis elegans

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