4838-35-1Relevant articles and documents
Novel green acylamide synthesis method through quaternary ammonium salt C-N bond fracture
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Paragraph 0072-0074, (2017/04/19)
The invention provides a novel green acylamide synthesis method through quaternary ammonium salt C-N bond fracture. The structure of the compound is expressed by methods such as H NMR, C, NMR and HRMS and is confirmed. A series of phenmethyl quaternary ammonium salts and aminated compounds are used; under the catalysis effect of PdCl2(dppf), PPh3 is used as a ligand, Na2CO3 is used as the alkali, and corresponding amide compounds are generated in the 100-DEG C CO atmosphere in a pHMe/DMSO mixed solvent. The method has the advantages that the efficiency is high; the toxicity is low; the conditions are mild; the application range of the substrate is wide; the yield is high; the product purity is high; the separation is convenient; the method can be applicable to large-scale preparation; the application prospects are wide.
Suzuki-Miyaura arylations of tetramic acid sulfonates: Evaluation of lactam protection, sulfonate esters, and sterics
Yoon-Miller, Sarah J. P.,Dorward, Kathryn M.,White, Kimberly P.,Pelkey, Erin T.
experimental part, p. 447 - 454 (2009/09/28)
(Chemical Equation Presented) The synthesis of 3,4-diaryl-3-pyrrolin-2-ones and 4-aryl-3-pyrrolin-2-ones using Suzuki-Miyaura cross-coupling reactions of tetramic acid sulfonates with arylboronic acids has been studied. The effect that sulfonate ester, st
3-ACYL-2-(N-CYANOIMINO)THIAZOLIDINES AS AN ACYLATING AGENT. PREPARATION OF AMIDES, ESTERS, AND THIOESTERS
Iwata, Chuzo,Watanabe, Mayumi,Okamoto, Shigeha,Fujimoto, Michitaro,Sakae, Masatoshi,et al.
, p. 323 - 326 (2007/10/02)
3-Acyl-2-(N-cyanoimino)thiazolidines proved to be powerful acylating agents.They reacted easily with amines, alcohols and thiols to give the corresponding amides, esters and thioesters in good yields.
