500-98-1

Basic information

• Product Name: PHENACETURIC ACID
• Synonyms: N-PHENYLACETYLGLYCINE;PHENACETURIC ACID;PHENYLACETYL GLYCINE;PHENYLAC-GLYCINE;PHENYLAC-GLY-OH;N-ALPHA-PHENYLACETYL-GLYCINE;2-(2-phenylacetyl)aminoacetic acid;Phenacetylglycine
• CAS NO: 500-98-1
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.2
• EINECS: 207-916-1
• Product Categories: Amino Acids & Derivatives;Aromatics;Metabolites & Impurities
• Mol File: 500-98-1.mol
• Article Data: 13

Chemical Properties

• Melting Point: 144°C
• Boiling Point: 476.5°Cat760mmHg
• Flash Point: 242°C
• Appearance: /
• Density: 1.239g/cm³
• Vapor Pressure: 6.93E-10mmHg at 25°C
• Storage Temp.: -15°C
• Solubility: Methanol (Slightly)
• PKA: 3.48±0.10(Predicted)
• CAS DataBase Reference: PHENACETURIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: PHENACETURIC ACID(500-98-1)
• EPA Substance Registry System: PHENACETURIC ACID(500-98-1)

Safety Data

• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 500-98-1(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

A metabolite of carboxylic acid.

Definition

ChEBI: A N-acylglycine that is glycine substituted on nitrogen with a phenylacetyl group.

InChI:InChI=1/C10H11NO3/c12-9(11-7-10(13)14)6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,12)(H,13,14)/p-1

Upstream product

• 103-82-2 phenylacetic acid 
• 4838-35-1 N-(phenylacetyl)glycine ethyl ester 
• 99-87-6 4-methylisopropylbenzene 
• 15545-34-3 methyl benzylpenillonate 
• 1555-80-2 phenylacetic anhydride 
• 56-40-6 glycine 
• 103-80-0 phenylacetyl chloride 
• 6000-44-8 sodium glycinate 
• 101-41-7 benzeneacetic acid methyl ester 
• 1078-60-0 2-benzyl-5(4H)-oxazolone 
• 28268-03-3 N-Carboxymethyl-phenylessigsaeure-amidoxim 
• 93769-19-8 3-(Phenylmethyl)-4H-1,2,4-oxadiazin-6(5H)-on 
• 23776-85-4 N-(phenylacetyl)oxysuccinimide 
• 60-29-7 diethyl ether 

Downstream Products

• 5259-87-0 methyl 2-(2-phenylacetamido)acetate 
• 4838-35-1 N-(phenylacetyl)glycine ethyl ester 
• 63257-00-1 N-(p-nitrophenylacetyl)-glycine 
• 15440-34-3 N-benzyl-2-(2-phenylacetamido)acetamide 
• 412035-63-3 acetoxy-(2-phenyl-acetylamino)-methane 
• 5874-59-9 N-phenylacetyl-glycine-anhydride 
• 100063-44-3 3-acetyl-2-benzyliden-oxazolidin-5-one 
• 881-90-3 4-benzylidene-2-methyl-2-oxazolin-5-one 
• 68662-93-1 2-benzyl-4-benzylidene-4H-oxazol-5-one 
• 61369-26-4 2-benzyl-4-ethoxymethylene-5-oxazolone 
• 15440-35-4 N-phenyl-N₂-(phenylacetyl)glycinamide 

Relevant articles and documents

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Development of a new enzyme-responsive self-immolative spacer conjugate applicable to the controlled drug release

A new self-immolative spacer conjugate based on a chemical adaptor unit aiming at controlled releasing drugs was designed and synthesized. It releases a fluorophore which was used as a model drug via a spontaneous cyclization mechanism after cleavage of an enzyme substrate. This system was proved to be stable under physiological conditions and only decomposed triggered by enzyme. It provides a generic linkage allowing connection of a variety of drugs and targeted devices to the chemical adaptor.

Novel synthesis and characterization of some new-2-(R) phenyl- 4-(-4-bromo-2-fluoro benzylidene)-oxazol-5-ones

In the present study a series of some new 2-(substituted) phenyl- 4-(4-bromo-2-fluoro benz-ylidene)-oxazol-5-ones (2a-2j) were synthesized by the condensation of selected substituted benzoyl glycine (1a-1j) with 4-bromo-2-fluoro benzaldehyde in the presence of fused sodium acetate and acetic anhydride. The constitution of the newly synthesized compounds has been supported by their physical properties, elemental analysis, colour, m.p, IR spectral analysis data.