486-89-5 Usage
Description
Anagyrine is a naturally occurring alkaloid that can be found in various plant species, such as Genista vuralli and Thermopsis rhombifolia. It is an amorphous substance with antimicrobial properties and has been identified in different forms, including perchlorate and picrate. Upon catalytic hydrogenation, anagyrine yields an octahydro derivative with distinct physical properties.
Uses
Used in Pharmaceutical Industry:
Anagyrine is used as an antimicrobial agent for its ability to inhibit the growth of various microorganisms. This property makes it a potential candidate for the development of new drugs and treatments targeting bacterial and fungal infections.
Used in Agricultural Industry:
Given its antimicrobial activity, anagyrine can also be utilized in the agricultural sector as a natural pesticide or fungicide to protect crops from diseases caused by harmful microorganisms, thereby increasing crop yield and reducing the reliance on synthetic chemicals.
Used in Research and Development:
Anagyrine's unique chemical properties and biological activities make it an interesting compound for further research and development. It can be studied for potential applications in various fields, including medicine, pharmacology, and biotechnology, to discover new therapeutic approaches and innovative solutions.
References
Manske, Marion., Can. J. Res., 20B, 265 (1942)
Manske, Marion., ibid, 21B, 144 (1943)
Check Digit Verification of cas no
The CAS Registry Mumber 486-89-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 486-89:
(5*4)+(4*8)+(3*6)+(2*8)+(1*9)=95
95 % 10 = 5
So 486-89-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H20N2O/c18-15-6-3-5-14-11-8-12(10-17(14)15)13-4-1-2-7-16(13)9-11/h3,5-6,11-13H,1-2,4,7-10H2/t11-,12+,13+/m0/s1
486-89-5Relevant articles and documents
The Enantioselective Total Synthesis of Bisquinolizidine Alkaloids: A Modular “Inside-Out” Approach
Scharnagel, Dagmar,Goller, Jessica,Deibl, Nicklas,Milius, Wolfgang,Breuning, Matthias
supporting information, p. 2432 - 2435 (2018/02/16)
Bisquinolizidine alkaloids are characterized by a chiral bispidine core (3,7-diazabicyclo[3.3.1]nonane) to which combinations of an α,N-fused 2-pyridone, an endo- or exo-α,N-annulated piperidin(on)e, and an exo-allyl substituent are attached. We developed a modular “inside-out” approach that permits access to most members of this class. Its applicability was proven in the asymmetric synthesis of 21 natural bisquinolizidine alkaloids, among them more than ten first enantioselective total syntheses. Key steps are the first successful preparation of both enantiomers of C2-symmetric 2,6-dioxobispidine by desymmetrization of a 2,4,6,8-tetraoxo precursor, the construction of the α,N-fused 2-pyridone by using an enamine-bromoacrylic acid strategy, and the installation of endo- or, optionally, exo-annulated piperidin(on)es.