490-63-1

Basic information

• Product Name: 2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID
• Synonyms: 2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID
• CAS NO: 490-63-1
• Molecular Formula: C₁₀H₁₀O₅
• Molecular Weight: 210.18
• Mol File: 490-63-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID(490-63-1)
• EPA Substance Registry System: 2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID(490-63-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 490-63-1(Hazardous Substances Data)

Usage

Description

2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID is a chemical compound with the molecular formula C11H12O5. It is a derivative of benzoic acid and contains a formyl group and two methoxy groups. 2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID is known for its versatility as a building block in the synthesis of more complex organic molecules, and its stability and availability make it a valuable tool for chemical and pharmaceutical research.

Uses

Used in Pharmaceutical Industry:
2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID is used as an intermediate in the synthesis of various pharmaceuticals for its potential biological and pharmacological activities. Its chemical properties allow it to be a key component in the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID is also used as an intermediate in the synthesis of agrochemicals, contributing to the development of pesticides, herbicides, and other agricultural chemicals that are essential for crop protection and yield enhancement.
Used in Research and Development:
In the field of research and development, 2-FORMYL-4,5-DIMETHOXY-BENZOIC ACID serves as a valuable compound for exploring its potential applications in various scientific and industrial areas. Its unique structure and properties make it an interesting subject for further studies and innovations.

Upstream product

• 531-88-4 5,6-dimethoxyphthalide 
• 408534-24-7 4,5-dimethoxy-2-oxalyl-benzoic acid 
• 147904-77-6 2-formyl-5-hydroxy-4-methoxy-benzoic acid 
• 74-88-4 methyl iodide 
• 7664-93-9 sulfuric acid 
• 40125-46-0 3-BROMO-5,6-DIMETHOXY-PHTHALIDE 
• 645-08-9 Isovanillic acid 
• 93-07-2 Veratric acid 
• 68-12-2 N,N-dimethyl-formamide 
• 6286-46-0 2-bromo-4,5-dimethoxybenzoic acid 

Downstream Products

• 56661-86-0 4,5-dimethoxy-2-(4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-benzoic acid 
• 103989-27-1 5,6-dimethoxy-3-nitromethyl-phthalide 
• 77394-23-1 3-[2-(2-Hydroxy-4,6-dimethoxy-phenyl)-2-oxo-ethyl]-5,6-dimethoxy-3H-isobenzofuran-1-one 
• 78865-56-2 6,7-Dimethoxy-2-(4-methoxy-phenyl)-2H-phthalazin-1-one 
• 79285-40-8 6,7-dimethoxy-2-phenylphthalazin-1(2H)-one 
• 78865-49-3 2-(2-chlorophenyl)-6,7-dimethoxy-1(2H)-phthalazinone 
• 78865-57-3 2-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-2H-phthalazin-1-one 
• 746-95-2 1-Oxo-1-<2-hydroxy-4-methoxy-phenyl>-3-<2-carboxy-4,5-dimethoxy-phenyl>-prop-2-en 
• 944252-33-9 2-bis(5-methyl-2-furyl)methyl-4,5-dimethoxybenzoic acid 
• 77394-24-2 Acetic acid 2-[2-(5,6-dimethoxy-3-oxo-1,3-dihydro-isobenzofuran-1-yl)-acetyl]-3,5-dimethoxy-phenyl ester 
• 77959-68-3 (5,6-dimethoxy-3-oxo-1,3-dihydro-isobenzofuran-1-yl)-triphenyl-phosphonium bromide 
• 560097-32-7 4-(N-methyl-methanesulphonamidomethyl)pyridine 
• 4821-88-9 6,7-dimethoxy-1(2H)-phthalazinone 
• 53012-84-3 2-formyl-4,5-dimethoxybenzoic acid methyl ester 

Relevant articles and documents

Synthesis of 3-Benzylphthalide Derivatives by Using a TDAE Strategy

A one-pot synthesis of new 3-benzylphthalide derivatives was developed by using a strategy based on tetrakis(dimethylamino)ethylene (TDAE). The reactions in the presence of TDAE of substituted benzyl chlorides with methyl 2-formylbenzoate or of substitute

Synthesis of chiral isoindolinones via asymmetric propargylation/lactamization cascade

A Zn-mediated propargylation/lactamization cascade reaction with chiral 2-formylbenzoate derived N-tert-butanesulfinyl imines was realized, which provided a practical and efficient method for the synthesis of chiral isoindolinones. High diastereoselectivities (up to 97:3 dr) and good reaction yields were observed for most examined cases.

Mild and efficient syntheses of diverse isoindolinones from ortho-phthaldehydic acid methylthiomethyl ester

A mild and efficient method for the synthesis of diverse isoindolinones from o-phthaldehydic acid methylthiomethyl ester and aliphatic/aromatic amines has been developed. A number of nucleophiles including a hydride ion were successfully added to the intermediate Schiff's base providing isoindolinones, with or without substitution at 3-position. Conditions have also been developed for amines with an integrated nucleophilic group to react in a diverse fashion either to give isoindolinones or tricyclic γ-lactams as single diastereoisomers in very good yield.