493-36-7 Usage
Description
2-[(3,4-Dihydroxyphenyl)methyl]-2,4,6-trihydroxy-3(2H)-benzofuranone, also known as Alphitonin, is a flavonoid compound derived from L. leptolepis wood. It serves as a metabolic intermediate in the catabolism of quercetin by the human gut bacteria E. ramulus. 2-[(3,4-Dihydroxyphenyl)methyl]-2,4,6-trihydroxy-3(2H)-benzofuranone is characterized by its unique chemical structure, which contributes to its potential applications in various fields.
Uses
Used in Pharmaceutical Applications:
Alphitonin is used as a pharmaceutical agent for its potential therapeutic properties. Its chemical structure allows it to interact with various biological targets, making it a candidate for the development of new drugs.
Used in Nutraceutical Applications:
Due to its presence in L. leptolepis wood and its formation during the catabolism of quercetin, Alphitonin can be utilized in the development of nutraceutical products. These products may offer health benefits by providing essential nutrients and promoting overall well-being.
Used in Research and Development:
Alphitonin's unique chemical structure and biological activity make it an interesting compound for research and development purposes. It can be used as a starting point for the synthesis of new compounds with potential applications in various industries, including pharmaceuticals, cosmetics, and agriculture.
Used in Cosmetic Applications:
The potential biological activity of Alphitonin may also make it a valuable ingredient in the cosmetic industry. It could be used in the development of skincare products, where its properties may contribute to improved skin health and appearance.
Check Digit Verification of cas no
The CAS Registry Mumber 493-36-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 493-36:
(5*4)+(4*9)+(3*3)+(2*3)+(1*6)=77
77 % 10 = 7
So 493-36-7 is a valid CAS Registry Number.
493-36-7Relevant articles and documents
Plasma-Induced Degradation of Quercetin Associated with the Enhancement of Biological Activities
Kim, Tae Hoon,Lee, Jaemin,Kim, Hyun-Joo,Jo, Cheorun
, p. 6929 - 6935 (2017/08/22)
Nonthermal plasma is a promising technology to improve the safety and to extend the shelf-life of various minimally processed foods. However, research on plasma-induced systemic degradation related to changes in chemical structure and biological activity is still very limited. In this study, the enhancement of biological activity and the mechanism of degradation of the most common type of flavonol, quercetin, induced by a dielectric barrier discharge (DBD) plasma were investigated. Quercetin is dissolved in methanol and exposed to nonthermal DBD plasma for 5, 10, 20, and 30 min. The quercetin treated with the plasma for 20 min showed rapidly increased α-glucosidase inhibitory and radical scavenging activities compared to those of parent quercetin. The structures of the degradation products 1-3 from the quercetin treated with the plasma for 20 min were isolated and characterized by interpretation of their spectroscopic data. Among the generated products, (±)-alphitonin (1) exhibited significantly improved antidiabetic and antioxidant properties compared to those of the parent quercetin. The antidiabetic and antioxidant properties were measured by α-glucosidase inhibition and 1,1-diphenyl-2-picrylhydrazyl radical scavenging assays. These results suggested that structural changes in quercetin induced by DBD plasma might be attributable to improving the biological activity.
