4945-26-0Relevant articles and documents
Palladium-catalyzed external-oxidant-free coupling reactions between isoquinoline/quinoline N-oxides with olefins
Guo, Tao,Liu, Yu,Zhao, Yun-Hui,Zhang, Pan-Ke,Han, Shu-Lei,Liu, Hong-Min
, p. 3920 - 3923 (2016)
A convenient and efficient approach for the synthesis of 1-alkenylisoquinolines and 2-alkenylquinolines was developed via palladium-catalyzed coupling reactions between isoquinoline/quinoline N-oxides with olefins under external-oxidant-free conditions. B
Manganese catalyzed C-alkylation of methylN-heteroarenes with primary alcohols
Jana, Akash,Kumar, Amol,Maji, Biplab
supporting information, p. 3026 - 3029 (2021/03/29)
C-Alkylations of nine different classes of methyl-substitutedN-heteroarenes, including quinolines, quinoxalines, benzimidazoles, benzoxazoles, pyrazines, pyrimidines, pyridazines, pyridines, and triazines are disclosed. A bench stable earth-abundant Mn(i)-complex catalyzed the chemoselective hydrogen-transfer reaction utilizing a diverse range of primary alcohols as the non-fossil fuel-derived carbon source. The diversifiedN-heteroarenes (41 examples) were isolated in high yields and selectivities. Water is produced as the sole byproduct, making the protocol environmentally benign.
Alkenylation or alkylation reaction method of alkyl-substituted aza-aromatic hydrocarbon
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Paragraph 0024-0034, (2020/07/02)
The invention discloses an alkenylation or alkylation reaction method of alkyl-substituted aza-aromatic hydrocarbon. According to the method, alkyl-substituted aza-aromatic hydrocarbon is used as a starting raw material, alcohol is used as an alkenylation or alkylation reagent, alkali is used as an accelerant, a nitrogen-containing or phosphine-containing ligand is used as an auxiliary agent, andan alkenylation or alkylation product is obtained under a heating condition. The method avoids the use of a transition metal catalyst, and has the advantages of easily available raw materials, simpleoperation, mild synthesis reaction conditions, high reaction efficiency, functional group diversity and the like.