4995-12-4

Basic information

• Product Name: 2-(4-Methoxyphenyl)pyrrole
• Synonyms: 2-(4-Methoxyphenyl)pyrrole;1H-Pyrrole, 2-(4-methoxyphenyl)-
• CAS NO: 4995-12-4
• Molecular Formula: C₁₁H₁₁NO
• Molecular Weight: 173.21114
• Mol File: 4995-12-4.mol
• Article Data: 26

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Methoxyphenyl)pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methoxyphenyl)pyrrole(4995-12-4)
• EPA Substance Registry System: 2-(4-Methoxyphenyl)pyrrole(4995-12-4)

Safety Data

• Hazardous Substances Data: 4995-12-4(Hazardous Substances Data)

Usage

General Description

2-(4-Methoxyphenyl)pyrrole, also known as 4-Methoxyphenyl-2-pyrrole, is a chemical compound consisting of a pyrrole ring with a 4-methoxyphenyl group attached to it. It is a heterocyclic compound with potential applications in the field of organic synthesis and pharmaceutical research due to its unique molecular structure and properties. 2-(4-Methoxyphenyl)pyrrole is often used as a building block in the synthesis of various organic compounds and is also being studied for its potential medicinal properties. Additionally, 2-(4-Methoxyphenyl)pyrrole has been investigated for its potential use as a pesticide due to its reported insecticidal activity. Overall, this chemical compound holds promise for various applications in the fields of chemistry, pharmacology, and agriculture.

Upstream product

• 56139-60-7 1-(4-Methoxyphenyl)-1,4-butandion 
• 2475-92-5 (E)-1-(4-methoxyphenyl)ethanone oxime 
• 107-06-2 1,2-dichloro-ethane 
• 2475-92-5 4-methoxyacetophenone oxime 
• 74-86-2 acetylene 
• 189079-91-2 4-Bromo-5-(4-methoxy-phenyl)-3,4-dihydro-2H-pyrrole 
• 198981-85-0 2-(4-methoxyphenyl)-1H-pyrrole-1-carboxylic acid 1,1-dimethylethyl ester 
• 517867-34-4 2,2-dimethylpropionic acid 1-ethoxythiocarbonylsulfanyl-4-(4-methoxyphenyl)-4-oxobutyl ester 
• 637354-46-2 2-(4-methoxyphenyl)-1-tosyl-1H-pyrrole 
• 109-97-7 pyrrole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 66897-25-4 4-methoxy-N-prop-2-enylbenzamide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 93624-01-2 O-ethyl S-2-(4-methoxyphenyl)-2-oxoethyl carbonodithioate 

Downstream Products

• 91735-79-4 2-(4-methoxyphenyl)-5-trifluoroacetylpyrrole 
• 864948-51-6 trimethyl 1,1'-bis-(4-methoxyphenyl)-5-(3-hydroxy-4-aminophenyl-N,N,O-triacetate)dipyrromethane 
• 937282-41-2 2-benzoyl-1-bromo-1,1-bis[5-(4-methoxyphenyl)-1H-pyrrol-2-yl]ethane 
• 937282-37-6 2-(2-benzoyl-1-bromoethenyl)-5-(4-methoxyphenyl)-1H-pyrrole 
• 1149735-84-1 1,3-bis(5-(3-methoxyphenyl)pyrrol-2-yl)-1,3-propanedione 
• 1363512-35-9 (Z)-methyl-4-((5-(4-methoxyphenyl)-1H-pyrrole-2-yl) (5-(4-methoxyphenyl)-2H-pyrrole-2-ylidene)methyl)benzoate 
• 1363520-28-8 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 
• 1363520-30-2 Bodipy-CO₂H 

Relevant articles and documents

Fabrication of Graphitic Carbon Nitride-Based Film: An Emerged Highly Efficient Catalyst for Direct C—H Arylation under Solar Light

Photoredox C—H bond formation can proceed in aerobic environment under solar light and has therefore become attractive. Nowadays, different types of expensive novel metal complexes and nanomaterials have been urbanized as photocatalysts for direct C—H bon

Isomer-Specific Hydrogen Bonding as a Design Principle for Bidirectionally Quantitative and Redshifted Hemithioindigo Photoswitches

A new class of bidirectionally quantitative photoswitches based on the hemithioindigo (HTI) scaffold is reported. Incorporation of a pyrrole hydrogen-bond donor leads to a bathochromic shift allowing for quantitative bidirectional isomerization. Additionally, extending conjugation from the electron-rich pyrrole results in quantitative visible-light photoswitches, as well as photoswitches that isomerize with red and near-infrared light. The presence of the hydrogen bond leading to the observed redshift is supported by computational and spectroscopic evidence.

Synthesis of 2-arylpyrroles via catalytic dehydrogenation of 2-aryl-1-pyrrolines in the presence of palladium-supported on alumina

A convenient synthesis of 2-arylpyrroles from the catalytic dehydrogenation of 2-aryl-1-pyrrolines in the presence of commercial palladium-supported on alumina (Pd/Al2O3) is described. The reaction scope was tested for aryl substituents with different steric hindrances and electronic natures. The dehydrogenation reaction conditions such as temperature, reflux time and amount of catalyst, revealed to be highly dependent on the 2-aryl substituent group, moderate to high yields and selectivities being obtained in a reaction involving straightforward work-up and purification procedures. In addition, the synthesis of the corresponding 2-aryl-1-pyrroline starting materials, through the cyclisation reaction involving 4-chlorobutyronitrile and aryl Grignard reagents, is also reported.