500206-01-9

Basic information

• Product Name: 2-fluoro-5-(4-morpholinyl)-Benzenamine
• Synonyms: 2-fluoro-5-(4-morpholinyl)-Benzenamine;2-Fluoro-5-morpholin-4-yl-phenylamine
• CAS NO: 500206-01-9
• Molecular Formula: C₁₀H₁₃FN₂O
• Molecular Weight: 196.2214232
• Mol File: 500206-01-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 372.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.232±0.06 g/cm3(Predicted)
• PKA: 5.30±0.40(Predicted)
• CAS DataBase Reference: 2-fluoro-5-(4-morpholinyl)-Benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-5-(4-morpholinyl)-Benzenamine(500206-01-9)
• EPA Substance Registry System: 2-fluoro-5-(4-morpholinyl)-Benzenamine(500206-01-9)

Safety Data

• Hazardous Substances Data: 500206-01-9(Hazardous Substances Data)

Upstream product

• 700804-64-4 2,2,2-trifluoro-N-(2-fluoro-5-morpholin-4-yl-phenyl)-acetamide 
• 369-36-8 6-fluoro-3-nitroaniline 
• 1542259-02-8 tert-butyl (2-fluoro-5-morpholinophenyl)carbamate 
• 454-07-9 N-(2-fluoro-5-nitrophenyl)acetamide 
• 75001-47-7 N-(5-amino-2-fluorophenyl)acetamide 

Downstream Products

• 700807-42-7 N₃-(2-fluoro-5-morpholin-4-yl-phenyl)-1-pyridin-2-yl-1H-[1,2,4]triazole-3,5-diamine 
• 1542257-76-0 3-(2-fluoro-5-morpholinophenyl)-2,6-dimethylpyrimidine-4(3H)-one 

Relevant articles and documents

Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins

The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.

CARBAZOLE AND CARBOLINE COMPOUNDS FOR USE IN THE DIAGNOSIS, TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH AMYLOID OR AMYOLID-LIKE PROTEINS

The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.

NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS

The present invention relates to the field of medicine, provided herein are novel nitrogenous heterocyclic compounds, their preparation methods and their uses as drugs, especially for treatment and prevention of tissue fibrosis. Also provided herein are pharmaceutically acceptable compositions comprising the nitrogenous heterocyclic compounds and the uses of the compositions in the treatment of human or animal tissue fibrosis, especially for human or animal renal interstitial fibrosis, glomerular sclerosis, liver fibrosis, pulmonary fibrosis, peritoneal fibrosis, myocardial fibrosis, dermatofibrosis, postsurgical adhesion, benign prostatic hyperplasia, skeletal muscle fibrosis, scleroderma, multiple sclerosis, pancreatic fibrosis, cirrhosis, myosarcoma, neurofibroma, pulmonary interstitial fibrosis, diabetic nephropathy, alzheimer disease or vascular fibrosis.