501432-17-3

Basic information

• Product Name: 2-Azidomethyl-benzoic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-(S)-thiiranyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester
• Synonyms: 2-Azidomethyl-benzoic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-(S)-thiiranyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester
• CAS NO: 501432-17-3
• Molecular Weight: 377.421
• Mol File: 501432-17-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Azidomethyl-benzoic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-(S)-thiiranyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azidomethyl-benzoic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-(S)-thiiranyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester(501432-17-3)
• EPA Substance Registry System: 2-Azidomethyl-benzoic acid (3aR,5S,6R,6aR)-2,2-dimethyl-5-(S)-thiiranyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester(501432-17-3)

Safety Data

• Hazardous Substances Data: 501432-17-3(Hazardous Substances Data)

Upstream product

• 289712-57-8 2-(azidomethyl)benzoic acid 
• 329781-57-9 methyl 2-(azidomethyl) benzoate 
• 34040-62-5 o-(chloromethyl)benzoic acid methyl ester 
• 87-41-2 2-benzofuran-1(3H)-one 
• 501432-18-4 2-Azidomethyl-benzoic acid (3aR,5S,6R,6aR)-5-((R)-2-acetoxy-1-acetylsulfanyl-ethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 

Downstream Products

• 501432-20-8 2-Azidomethyl-benzoic acid (3aS,4aR,8aS,9S,9aR)-2,2,7,7-tetramethyl-hexahydro-[1,3]dioxolo[4',5':5,6]thiopyrano[3,2-d][1,3]dioxin-9-yl ester 
• 501432-19-5 2-Azidomethyl-benzoic acid (2S,3R,4S,5S,6R)-2,3,5-trihydroxy-6-hydroxymethyl-tetrahydro-thiopyran-4-yl ester 
• 501432-18-4 2-Azidomethyl-benzoic acid (3aR,5S,6R,6aR)-5-((R)-2-acetoxy-1-acetylsulfanyl-ethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 

Relevant articles and documents

Novel preparation of (2-azidomethyl)benzoic acid and an application as a protective group

A novel preparation method of 2-(azidomethyl)benzoic acid, a precursor of (2-azidomethyl)benzoyl (AZMB) protective group, was developed which can provide pure sample in gram scale without chromatographic purifications. Reductive cleavage using triphenylphosphine was found to be effective in the case of sterically hindered ester that resists under basic hydrolysis.