501948-42-1Relevant articles and documents
Application of DMF-methyl sulfate adduct in the regioselective synthesis of 3-acylated indolizines
Przewloka, Teresa,Chen, Shoujun,Xia, Zhiqiang,Li, Hao,Zhang, Shijie,Chimmanamada, Dinesh,Kostik, Elena,James, David,Koya, Keizo,Sun, Lijun
, p. 5739 - 5742 (2008/02/09)
A number of 3-acylated indolizines were synthesized in good to excellent yields by a newly established reaction between picolinium salts and the methylsulfate salt of A (R = Me), the adduct formed from DMF-Me2SO4 as the key reagent.
Controlling chemoselectivity-application of DMF di-t-butyl acetal in the regioselective synthesis of 3-monosubstituted indolizines
Xia, Zhiqiang,Przewloka, Teresa,Koya, Keizo,Ono, Mitsunori,Chen, Shoujun,Sun, Lijun
, p. 8817 - 8820 (2007/10/03)
Among a number of DMF dialkyl acetals investigated for the regioselective synthesis of 3-acylindolizines, the di-t-butyl acetal, via its iminium intermediate readily formed in situ, provides the highest chemoselectivity for the intermolecular cyclization of picolinium salts. DMF di-t-butyl acetal was applied to the syntheses of a variety of 3-acylated indolizines including alkyl, aryl, and heteroaryl substituents.
1-Glyoxlylamide indolizines for treating cancer
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, (2008/06/13)
Disclosed is a compound represented by Structural Formula (I): Ring A is substituted or unsubstituted and optionally fused to an aryl group. Z1 and Z2 are independently ═O, ═S, ═N—OR12 or ═NR12 R1 an
