4909-78-8 Usage
Description
N,N-Dimethylformamide dineopentyl acetal is a colorless to slightly yellow liquid that serves as a versatile reagent in various chemical reactions. It is particularly useful in the lactonization of ω-hydroxyacids, converting primary alcohols into alkylating agents, and in the esterification of Nα-9-fluorenylmethyloxycarbonylamino acids. Additionally, it has been employed in the synthesis of various barbiturate derivatives and in the stereospecific labeling of L-serine and L-cystine with deuterium at the β-position.
Uses
Used in Chemical Synthesis:
N,N-Dimethylformamide dineopentyl acetal is used as a reagent for the lactonization of ω-hydroxyacids, enabling the formation of lactones with up to 16-membered rings. This application is crucial for the synthesis of various complex organic compounds and pharmaceuticals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N-Dimethylformamide dineopentyl acetal is used as a reagent for the conversion of primary alcohols into alkylating agents. These alkylating agents are essential for the alkylation of thiols, a process that plays a significant role in the synthesis of various drugs and therapeutic agents.
Used in Peptide Synthesis:
N,N-Dimethylformamide dineopentyl acetal is utilized in the esterification of Nα-9-fluorenylmethyloxycarbonylamino acids, a critical step in the synthesis of peptides and proteins. This application is vital for the development of new drugs and the study of protein structure and function.
Used in Barbiturate Synthesis:
In the chemical industry, N,N-Dimethylformamide dineopentyl acetal is used in the synthesis of 1,3-dialkyl, benzyl, and cyclohexyl barbiturate derivatives. These barbiturates are important components in the formulation of various sedatives, hypnotics, and anesthetics.
Used in Deuterium Labeling:
N,N-Dimethylformamide dineopentyl acetal is employed as a reagent during the synthesis of L-serine and L-cystine stereospecifically labeled with deuterium at the β-position. This technique is valuable for studying the structure and dynamics of these amino acids and their role in various biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 4909-78-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,0 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4909-78:
(6*4)+(5*9)+(4*0)+(3*9)+(2*7)+(1*8)=118
118 % 10 = 8
So 4909-78-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H29NO2/c1-12(2,3)9-15-11(14(7)8)16-10-13(4,5)6/h11H,9-10H2,1-8H3/p+1
