83638-46-4

Basic information

• Product Name: 8-[2-(3,5-Dimethoxy-phenyl)-ethylidene]-1,4-dioxa-spiro[4.5]decane
• CAS NO: 83638-46-4
• Molecular Weight: 304.386
• Mol File: 83638-46-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-[2-(3,5-Dimethoxy-phenyl)-ethylidene]-1,4-dioxa-spiro[4.5]decane(CAS DataBase Reference)
• NIST Chemistry Reference: 8-[2-(3,5-Dimethoxy-phenyl)-ethylidene]-1,4-dioxa-spiro[4.5]decane(83638-46-4)
• EPA Substance Registry System: 8-[2-(3,5-Dimethoxy-phenyl)-ethylidene]-1,4-dioxa-spiro[4.5]decane(83638-46-4)

Safety Data

• Hazardous Substances Data: 83638-46-4(Hazardous Substances Data)

Upstream product

• 637-88-7 1,4-Cyclohexanedione 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 83638-32-8 1-(3,5-dimethoxyphenylethyl)-4-oxocyclohexanol ethylene acetal 
• 4909-78-8 N,N-dimethylformamide dineopentyl acetal 

Relevant articles and documents

1,2-Disubstituted Ethanes As Possible Precursors For The Synthesis of Cannabis Spirans

Three possible methods for converting suitable 1,2-disubstituted ethanes into Cannabis spirans have been investigated. 4',5-Dihydroxy-3-methoxybibenzyl underwent intramolecular o-p- and p-p-coupling with ferricyanide in a chloroform-aqueous potassium carbonate system, but yields were low: certain other oxidants did not succeed or gave only traces of product.A method for making 1-hydroxy-1-(3,5-dimethoxyphenylethyl)cyclohexan-4-one ethylene acetal or thioacetal via a Birch reaction is described: despite favourable precedent, acid-catalysed cyclisation led to octahydrophenanthrenones rather than spiro-ketones, whilst N,N-dimethylformamide dineopentyl acetal gave two olefins.Jacquesy's super-asid method for making spirocyclohexenones from a methoxylated bibenzyl was not applicable to the 3,4',5-trimethoxy-case, which would have given cannabispirenone methyl ether, presumably because of protonation of both aromatic systems.