502-33-0Relevant articles and documents
Total synthesis and biological evaluation of methylgerambullone
Moon, Jong Taik,Ha, Sung Hoon,Lee, So Hyung,Kwon, Tae Hui,Oh, Chun Rim,Kim, Young Deuk,Kim, Jungahn,Choo, Dong Joon,Lee, Jae Yeol
scheme or table, p. 52 - 55 (2010/04/24)
First total synthesis of methylgerambullone (MGB, 1) isolated from Glycosmis angustifolia was completed via a convergent route. The effect of MGB on the contractile responses of the isolated guinea-pig ileum induced by acetylcholine was investigated. As a result, it showed a potent relaxation rate (78.66 ± 4.30% at 100 mg/L) in a concentration-dependent manner on longitudinal smooth muscle contraction of isolated guinea-pig ileum induced by 1 μM acetylcholine.
Reactions with α,β-Unsaturated Nitrile Oxides. Synthetic Studies in the Terpene Field. Synthesis of Tagetones, Ocimenones, Deodarone and Atlantone
Isager, Per,Thomsen, Ib,Torssell, Kurt B. G.
, p. 806 - 813 (2007/10/02)
The generation and 1,3-dipolar cycloaddition of α,β-unsaturated nitrile oxides are described.Selective reductive cleavage of the isoxazoline ring was achived.Subsequent elimination of water leads to the 1,4-dien-3-one system.The formation of tetrahydro-γ-pyrones is observed.The reactions were applied to the synthesis of tagetones, ocimenones, deodarone and atlantone.
Terpenes and Terpene Derivatives, XVII. - Thermal and AlCl3-Catalyzed Reaction of Ocimenone
Weyerstahl, Peter,Zombik, Winfried,Gansau, Christian
, p. 422 - 427 (2007/10/02)
Bis(trans-ocimenone) (5),reported to be a naturally occuring compound, is formed by thermal dimerization of (E)-ocimenone (E-4). - Treatment of 4 with AlCl3 leads, in addition to unchanged 4, to a mixture of the rearranged products filifolone (6) and rac-