50333-45-4

Basic information

• Product Name: 4-AZEPAN-1-YLBENZALDEHYDE
• Synonyms: 4-AZEPAN-1-YLBENZALDEHYDE
• CAS NO: 50333-45-4
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.28
• Mol File: 50333-45-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly)
• Stability: Air Sensitive, Hygroscopic
• CAS DataBase Reference: 4-AZEPAN-1-YLBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AZEPAN-1-YLBENZALDEHYDE(50333-45-4)
• EPA Substance Registry System: 4-AZEPAN-1-YLBENZALDEHYDE(50333-45-4)

Safety Data

• Hazardous Substances Data: 50333-45-4(Hazardous Substances Data)

Usage

Uses

4-(Azepan-1-yl)benzaldehyde can be used to improve the performance of a photorefractive device by utilizing electrolytes.

Upstream product

• 111-49-9 hexamethylene imine 
• 459-57-4 4-fluorobenzaldehyde 
• 162377-67-5 4-(Hexahydroazepin-1-yl)benzonitrile 

Downstream Products

• 742698-90-4 3-(4-azepan-1-yl-phenyl)-acrylic acid ethyl ester 

Relevant articles and documents

Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging

The dimethylamino group of AkaLumine ((4S)-2-[(1E,3E)-4-[4-(dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-4-thiazolecarboxylic acid), a red-light-emitting firefly luciferin analogue, was replaced by cyclic amino groups (1-pyrrolidinyl, 1-piperidino, 1-azepanyl, and 4-morpholino) to give AkaLumine analogues exhibiting desirable bioluminescence with emission maxima in the red region (656–667 nm). In particular, a bioluminescence reaction of 1-pyrrolidinyl analogue with a recombinant Photinus pyralis luciferase showed a higher quantum yield than that with AkaLumine, giving an improved bioluminescence intensity. The 1-pyrrolidinyl analogue also showed the strongest luminescence in whole-body luciferase-expressing mice among the analogues, indicating that a quantum yield improvement of a luciferin analogue is effective to increase bioluminescence imaging intensity.

QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR

This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.

Ultrasound effect on the synthesis of 4-alkyl-(aryl)aminobenzaldehydes

The sonochemical nucleophilic aromatic substitutions on 4-fluorobenzaldehyde with different azacycloalkanes and azoles have been studied. A beneficial ultrasound effect was observed, reactions were clean and high yields of the products were isolated after 15 min sonication.