50670-76-3

Basic information

• Product Name: ETHYL 4'-HYDROXY-4-BIPHENYLCARBOXYLATE
• Synonyms: ETHYL 4'-HYDROXY-4-BIPHENYLCARBOXYLATE;1,1''-Bicyclo-4-hexanone-4''-carboxylic acid ethyl ester;Ethyl 4'-hydroxy[1,1'-biphenyl]-4-carboxylate;4-(4-Ethoxycarbonylphenyl)phenol;4Hydroxy-4-biphenyl-4-carboxylic acid ethyl ester;Ethyl 4'-hydroxybiphenyl-4-carboxylate
• CAS NO: 50670-76-3
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 252.35
• Product Categories: E-F;Stains and Dyes;Stains&Dyes, A to
• Mol File: 50670-76-3.mol
• Article Data: 26

Chemical Properties

• Melting Point: 142-144 °C (dec.)(lit.)
• Boiling Point: 392.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.167±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.56±0.26(Predicted)
• CAS DataBase Reference: ETHYL 4'-HYDROXY-4-BIPHENYLCARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4'-HYDROXY-4-BIPHENYLCARBOXYLATE(50670-76-3)
• EPA Substance Registry System: ETHYL 4'-HYDROXY-4-BIPHENYLCARBOXYLATE(50670-76-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 50670-76-3(Hazardous Substances Data)

Usage

Uses

4-(4-Ethoxycarbonylphenyl)phenol. Dyes and metabolites.

Upstream product

• 64-17-5 ethanol 
• 58574-03-1 4'-Hydroxybiphenyl-4-carboxylic acid 
• 74-96-4 ethyl bromide 
• 148-86-7 4-acetoxybiphenyl 
• 29558-77-8 4-bromo-4'-hydroxybiphenyl 
• 58743-83-2 4-bromo-4'-methoxylbiphenyl 
• 725-14-4 4'-methoxy-biphenyl-4-carboxylic acid 
• 84244-98-4 4'-bromobiphenyl-4-yl acetate 
• 14062-25-0 Ethyl 4-bromophenylacetate 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 540-38-5 p-Iodophenol 
• 4334-88-7 p-ethoxycarbonylphenylboronic acid 
• 19812-93-2 4-Cyano-4'-hydroxybiphenyl 
• 571903-64-5 4-(ethoxycarbonyl)phenylmagnesium chloride 

Downstream Products

• 439610-75-0 4-(3-benzyloxyprop-1-oxy)biphenyl-4'-carboxylic acid 
• 158548-58-4 ethyl 4'-(10-undecen-1-yloxy)-1,1'-biphenyl-4-carboxylate 
• 947669-86-5 ethyl 4'-(methyl(3-(pyridin-4-yl)benzyl)carbamoyloxy)biphenyl-4-carboxylate 
• 878002-90-5 C₂₇H₃₀O₅ 
• 811803-89-1 C₂₅H₂₆O₅ 
• 811803-93-7 C₂₉H₃₄O₅ 

Relevant articles and documents

Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES)

We report the initial results of our study into a series of simple 4′-O-sulfamoyl-4-biphenyl based compounds as novel inhibitors of the enzyme estrone sulfatase (ES). The results of the study show that these compounds are potent inhibitors, possessing greater inhibitory activity than COUMATE, but weaker inhibitory activity than EMATE or the tricyclic derivative of COUMATE, namely 667-COUMATE. Furthermore, the compounds are observed to be irreversible inhibitors.

Iron-Catalyzed Room Temperature Cross-Couplings of Bromophenols with Aryl Grignard Reagents

Herein we report a room temperature Fe-catalyzed coupling reaction of various bromophenols with aryl Grignard reagents, which exhibits a wide substrate scope and high functional group tolerance. For the first time, the combination of simple Fe(acac)3/PBu3/Ti(OEt)4 has been used as an effective catalyst for the biaryl couplings of bromophenols or their Na or K salts with debromination and etherification side reactions being well suppressed. Various biphenols including natural product garcibiphenyl C as well as pharmaceutical diflunisal and its ethyl ester were facilely synthesized using the present protocol. (Figure presented.).

NOVEL AZO-BASED DICHROIC DYE, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT COMPRISING THE AZO-BASED DICHROIC DYE

PROBLEM TO BE SOLVED: To provide a novel azo-based dichroic dye having improved solubility with a host liquid crystal while maintaining a high order parameter (S value), and a liquid crystal composition and a liquid crystal element or the like capable of

DICHROIC DYE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT

PROBLEM TO BE SOLVED: To provide a novel azo dichroic dye having solubility for practical use while maintaining high contrast order parameter (S value). SOLUTION: There is provided azo dichroic dye represented by the formula (I), where Ar1 to A1 are each independently a substituted/unsubstituted 1,4-phenylene group, a substituted/unsubstituted naphthylene group or a substituted/unsubstituted (E)-cyclohexane-1,4-diyl group, X1 is a direct bond or a bivalent group, L1 is a direct bond or a bivalent group containing no cyclic structure nor azo bond, B1 and B2 are direct bond or bivalent group containing no cyclic structure nor azo bond and Y1 and Y2 are specific general formulae. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2017,JPO&INPIT