509-72-8

Basic information

• Product Name: Fluoran, 3,6-diamino-
• CAS NO: 509-72-8
• Molecular Formula: C₂₀H₁₄N₂O₃
• Molecular Weight: 330.343
• Mol File: 509-72-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Fluoran, 3,6-diamino-(CAS DataBase Reference)
• NIST Chemistry Reference: Fluoran, 3,6-diamino-(509-72-8)
• EPA Substance Registry System: Fluoran, 3,6-diamino-(509-72-8)

Safety Data

• Hazardous Substances Data: 509-72-8(Hazardous Substances Data)

Usage

General Description

Fluoran, 3,6-diamino- is a chemical compound that belongs to the family of organic dyes. It is commonly used as a fluorescent marker in biological and medical applications, such as labeling nucleic acids and proteins in microscopy and flow cytometry. Fluoran, 3,6-diamino- has a high affinity for binding to DNA and RNA, making it useful in studying the structure and function of nucleic acids. Its fluorescent properties make it easy to visualize and track the movement of biological molecules in living cells. However, it is important to handle this chemical with care, as it may have toxic and mutagenic effects on living organisms.

Upstream product

• 85-44-9 phthalic anhydride 
• 591-27-5 m-Hydroxyaniline 
• 509-34-2 rhodamine B 
• 121-47-1 3-aminobenzenesulfonic acid 

Downstream Products

• 2321-07-5 fluorescein 
• 1140465-77-5 N,N'-Boc-Hph-rhodamine 110 
• 897929-08-7 3'-amino-6'-(tert-butoxycarbonylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one 
• 1433896-28-6 rhodamine(Arg-(CBz)2-NHBoc)₂ 
• 1429788-65-7 C₃₂H₃₂N₄O₇S₂ 
• 1346550-27-3 C₂₅H₁₉N₃O₄ 
• 1346550-26-2 C₃₀H₂₇N₃O₆ 
• 1346550-28-4 C₃₅H₂₈N₄O₁₀ 
• 1027627-68-4 azido-Rh₁₁₀-t-Boc 
• 1311393-87-9 C₂₅H₁₉N₅O₅ 
• 628302-72-7 N-Mor-rhodamine 110 

Relevant articles and documents

Atomically Conformal Metal Laminations on Plasmonic Nanocrystals for Efficient Catalysis

Despite the enormous application potential, methods for conformal few-atomic-layer deposition on colloidal nanocrystals (NCs) are scarce. Similar to the process of lamination, we introduce a confine and shine strategy to homogeneously modify the different surface curvatures of plasmonic NCs with ultrathin conformal layers of diverse catalytic noble metals. This self-limited epitaxial skinlike metal growth harvests the localized surface plasmon resonance to induce reduction chemistry directly on the NC surface, confined inside hollow silica. This strategy avoids any kinetic anisotropic metal deposition. Unlike the conventional thick, anisotropic, and dendritic shells, which show severe nonradiative damping, the skinlike metal lamination preserves the key plasmonic properties of the core NCs. Consequently, the plasmonic-catalytic hybrid nanoreactors can carry out a variety of organic reactions with impressive rates.

Triarylmethane Fluorophores Resistant to Oxidative Photobluing

Spectral stability of small-molecule fluorescent probes is required for correct interpretation and reproducibility of multicolor fluorescence imaging data, in particular under high (de)excitation light intensities of super-resolution imaging or in single-molecule applications. We propose a synthetic approach to a series of spectrally stable rhodamine fluorophores based on sequential Ru- and Cu-catalyzed transformations, evaluate their stability against photobleaching and photoconversion in the context of other fluorophores using chemometric analysis, and demonstrate chemical reactivity of fluorophore photoproducts. The substitution patterns providing the photoconversion-resistant triarylmethane fluorophores have been identified, and the applicability of nonbluing labels in live-cell STED nanoscopy is demonstrated.