897929-08-7

Basic information

• Product Name: 3'-amino-6'-(tert-butoxycarbonylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
• Synonyms: 3'-amino-6'-(tert-butoxycarbonylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
• CAS NO: 897929-08-7
• Molecular Weight: 430.46
• Mol File: 897929-08-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3'-amino-6'-(tert-butoxycarbonylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-amino-6'-(tert-butoxycarbonylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one(897929-08-7)
• EPA Substance Registry System: 3'-amino-6'-(tert-butoxycarbonylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one(897929-08-7)

Safety Data

• Hazardous Substances Data: 897929-08-7(Hazardous Substances Data)

Upstream product

• 509-72-8 3',6'-diamino-spiro[phthalan-1,9'-xanthen]-3-one 
• 24608-52-4 tert-butyl chloroformate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1346550-28-4 C₃₅H₂₈N₄O₁₀ 

Relevant articles and documents

A caged, localizable rhodamine derivative for superresolution microscopy

A caged rhodamine 110 derivative for the specific labeling of SNAP-tag fusion proteins is introduced. The caged rhodamine 110 derivative permits the labeling of cell surface proteins in living cells and of intracellular proteins in fixed cells. The probe requires only a single caging group to maintain the fluorophore in a non-fluorescent state and becomes highly fluorescent after uncaging. The high contrast ratio is confirmed both in bulk and at the single molecule level. This property, together with its high photon yield makes it an excellent dye for photoactivated localization microscopy (PALM), as we demonstrate here.

FLUORESCENT MOLECULE

It is an object of the present invention to provide an on-off type fluorescent compound used in gene analyses, which is highly stable and highly sensitive, and which enables amplification of a trace amount of gene signal and observation thereof. The present invention provides a compound represented by the following formula (1) or (2): wherein R1 represents an alkyl group containing 1 to 6 carbon atoms, an amino group, an amide group optionally having a protecting group or a substituent, a halogen atom, or a hydrogen atom; R2 independently represents an alkyl group containing 1 to 6 carbon atoms, a halogen atom, or a hydrogen atom; R3 represents an alkyl group containing 1 to 6 carbon atoms, an aryl group, or a hydrogen atom; R4 represents a group containing an oxygen atom, or a hydrogen atom, wherein R3 may bind to R4 to form a ring.