50986-93-1

Basic information

• Product Name: 1-(phenylsulfinyl)-4-(trifluoromethyl)benzene
• Synonyms: 1-(phenylsulfinyl)-4-(trifluoromethyl)benzene
• CAS NO: 50986-93-1
• Molecular Weight: 270.275
• Mol File: 50986-93-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(phenylsulfinyl)-4-(trifluoromethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(phenylsulfinyl)-4-(trifluoromethyl)benzene(50986-93-1)
• EPA Substance Registry System: 1-(phenylsulfinyl)-4-(trifluoromethyl)benzene(50986-93-1)

Safety Data

• Hazardous Substances Data: 50986-93-1(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 7417-81-4 benzyl phenyl sulfoxide 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 5427-04-3 diphenylmethyl phenyl sufoxide 
• 85533-19-3 1-benzenesulfinyl-2-trimethylsilylethane 
• 53451-90-4 phenyl 4-trifluoromethylphenyl sulfide 
• 591-50-4 iodobenzene 
• 2211-92-9 di-tert-butyl sulfoxide 
• 455-13-0 4-Iodobenzotrifluoride 
• 825-83-2 4-trifluoromethylbenzenethiol 
• 62076-10-2 (tert-butylsulfinyl)benzene 
• 108-98-5 thiophenol 
• 25752-91-4 2-methyl-2-propyl 4-trifluoromethylphenyl sulfide 

Relevant articles and documents

Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides

The oxidation of diaryl sulfides and aryl alkyl sulfides to the corresponding sulfoxides and sulfones under electrochemical conditions is reported. Sulfoxides are selectively obtained in good yield under a constant current of 5 mA for 10 h in DMF, while sulfones are formed as the major product under a constant current of 10 or 20 mA for 10 h in MeOH. The oxygen of both the sulfoxide and sulfone function is derived from water.

Tert-Butyl Sulfoxides: Key Precursors for Palladium-Catalyzed Arylation of Sulfenate Salts

The present report describes an efficient and clean generation of sulfenate salts (R1SO-) by pyrolysis of readily available tert-butyl sulfoxides to give sulfenic acids (R1SOH) and traceless isobutene, followed by hydrogen abstraction with a weak inorganic base (K3PO4). The relevance of this process was exemplified through an in situ palladium-catalyzed cross-coupling reaction with aryl halides/triflates leading to aryl sulfoxides. The operationally simple C-S bond-forming protocol developed uses Pd(dba)2 as catalyst and Xantphos as ligand in toluene or a toluene/H2O mixture. Further extensions include the use of di-tert-butyl sulfoxide as an equivalent for sulfur monoxide dianion (SO2-) and the development of diastereoselective versions in the [2.2]paracyclophane and biaryl series.