510-20-3

Basic information

• Product Name: DIETHYLMALONIC ACID
• Synonyms: DIETHYLMALONIC ACID;2,2-Diethylmalonic acid;3,3-Pentanedicarboxylic acid;diethyl-propanedioicaci;Malonic acid, diethyl-;RARECHEM AL BO 2167;DiethylMalonateGr;DiethylMalonateForSynthesis
• CAS NO: 510-20-3
• Molecular Formula: C₇H₁₂O₄
• Molecular Weight: 160.17
• EINECS: 208-111-8
• Product Categories: Carboxylic Acid Monomers;Monomers;Polymer Science
• Mol File: 510-20-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 129-131 °C(lit.)
• Boiling Point: 328.8°C (rough estimate)
• Flash Point: 61 °C
• Appearance: /
• Density: 1.3681 (rough estimate)
• Vapor Pressure: 5.2E-05mmHg at 25°C
• Refractive Index: 1.4336 (estimate)
• Storage Temp.: 2-8°C
• PKA: pK1:2.151;pK2:7.417 (25°C)
• Merck: 13,3151
• BRN: 1768554
• CAS DataBase Reference: DIETHYLMALONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYLMALONIC ACID(510-20-3)
• EPA Substance Registry System: DIETHYLMALONIC ACID(510-20-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 510-20-3(Hazardous Substances Data)

Usage

Uses

Diethylmalonic acid is used in chemistry as a buffer with a capacity of pH values above 5.8.

InChI:InChI=1/C7H12O4/c1-3-7(4-2,5(8)9)6(10)11/h3-4H2,1-2H3,(H,8,9)(H,10,11)

Upstream product

• 57-44-3 diethylbarbituric acid 
• 1634-72-6 2-ethyl-2-(hydroxymethyl)butanal 
• 75-03-6 ethyl iodide 
• 105-53-3 diethyl malonate 
• 77-25-8 diethyl diethylmalonate 
• 29141-71-7 2,2-Diethyl-malonamide 
• 736-78-7 1-benzoyl-5,5-diethyl-pyrimidine-2,4,6-trione 
• 33376-32-8 5,5-diethyl-dihydro-pyrimidine-4,6-dione 
• 7732-18-5 water 
• 77-32-7 thiobarbital 
• 52927-25-0 diethylthiomalonuric acid 
• 7697-37-2 nitric acid 
• 39623-07-9 isopropylidene diethylmalonate 

Downstream Products

• 27132-23-6 diethylmalonic acid dimethyl ester 
• 77-25-8 diethyl diethylmalonate 
• 6832-96-8 2-ethyl-N-phenylbutanamide 
• 88-09-5 2-Ethylbutanoic acid 
• 15719-64-9 methylammonium carbonate 
• 5456-23-5 2-ethyl-2-bromo-butyric acid 
• 54505-72-5 diethylmalonyl chloride 
• 2274-01-3 N-carbamoyl-2-ethylbutyraldehyde 
• 102172-16-7 diethyl-malonic acid diphenyl ester 
• 84836-32-8 2-Ethyl-1-(4-methoxy-phenyl)-butan-1-one 
• 50390-52-8 2-ethyl-1-(p-tolyl)butan-1-one 
• 64289-52-7 2-amino-5,5-diethyl-1H-pyrimidine-4,6-dione 
• 64289-52-7 acide diethyl-5,5 imino-2 barbiturique 
• 3639-21-2 2-ethyl-2-hydroxybutyric acid 

Relevant articles and documents

Synthesis and cyclization of dialkylmalonuric esters

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Copper(II)-catalyzed enantioselective intramolecular cyclization of N-alkenylureas

The first Cu(II)-catalyzed highly enantioselective intramolecular cyclization of N-alkenylureas was developed for the concise assembly of chiral vicinal diamino bicyclic heterocycles. Facile removal of carbonyl group of the carbamido moiety allowed for ready access to enantioenriched cyclic vicinal diamines.

Phenylalanine derivatives

Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α 4 integrin. They are used as therapeutic agents for various diseases concerning α 4 integrin.