51186-58-4 Usage
Description
Boc-D-aspartic acid 4-benzyl ester, also known as N-Boc-D-aspartic acid 4-benzyl ester, is a chemical compound derived from aspartic acid, an amino acid found in proteins. It is characterized by the presence of a benzyl ester group and a Boc (tert-butyloxycarbonyl) protecting group. Boc-D-aspartic acid 4-benzyl ester is widely utilized in the synthesis of various organic and pharmaceutical compounds due to its unique structural features and reactivity.
Uses
Used in Organic Synthesis:
Boc-D-aspartic acid 4-benzyl ester is used as an intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows for selective reactions and functional group manipulations, making it a valuable building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Boc-D-aspartic acid 4-benzyl ester is used as an intermediate in the synthesis of drugs and drug candidates. Its incorporation into drug molecules can provide specific biological activities or improve the pharmacokinetic properties of the final product, such as solubility, stability, or bioavailability.
Used in Research and Development:
Boc-D-aspartic acid 4-benzyl ester is also employed in research and development for the study of various biological processes and the development of new therapeutic strategies. Its unique structural features make it an attractive candidate for the design and synthesis of novel bioactive molecules with potential applications in medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 51186-58-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,1,8 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 51186-58:
(7*5)+(6*1)+(5*1)+(4*8)+(3*6)+(2*5)+(1*8)=114
114 % 10 = 4
So 51186-58-4 is a valid CAS Registry Number.
51186-58-4Relevant articles and documents
Degradation-promoters of cellular inhibitor of apoptosis protein 1 based on bestatin and actinonin
Sato, Shinichi,Tetsuhashi, Masashi,Sekine, Keiko,Miyachi, Hiroyuki,Naito, Mikihiko,Hashimoto, Yuichi,Aoyama, Hiroshi
, p. 4685 - 4698 (2008/12/20)
A series of hybrid compounds of bestatin (1) and actinonin (3), which promote degradation of cellular inhibitor of apoptosis protein 1 (cIAP1), were designed and synthesized. Structure-activity relationship studies indicated that absolute configuration, hydrophobicity at the α-position of the internal amide carbonyl group, and the presence of a small substituent at the α-position of the ester group are important factors for the expression of potent cIAP1 degradation-promoting activity. HAB-5A (30b) showed the most potent activity (IC50 = 0.53 μM) among the compounds prepared.
Novel immunological adjuvant compounds and methods of preparation thereof
-
, (2008/06/13)
This application relates to novel immunological adjuvant compounds of the formula: STR1 wherein each of R and R1 are the same or different and are hydrogen or an acyl radical; R2 is an unsubstituted or substituted alkyl radical, or an unsubstituted or substituted aryl radical; X is an aminoacyl moiety; and Y is D-isoasparagine or D-isoglutamine.
