512173-24-9Relevant articles and documents
Direct amide bond formation from carboxylic acids and amines using activated alumina balls as a new, convenient, clean, reusable and low cost heterogeneous catalyst
Ghosh, Sabari,Mukhopadhyay, Chhanda,Bhaumik, Asim,Mondal, John,Mallik, Amit,Sengupta, Sumita
, p. 3220 - 3229,10 (2020/09/16)
For the first time, we have used activated alumina balls (3-5 mm diameter) for amide synthesis from carboxylic acids (unactivated) and amines (unactivated) under neat reaction conditions that produce no toxic by-products and has the advantages of being low-cost, easily available, heterogeneous, reusable and environmentally benign with no troublesome/hazardous disposal of the catalyst.
Catalytic transamidation and amide metathesis under moderate conditions
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Page 3; Sheet 5, (2008/06/13)
Disclosed is a method of manipulating the carboxamide functionality in a catalytic manner. The method includes the steps of reacting amides with or without amines in the presence of various types of metal catalysts, at a temperature of about 250° C. or less.