512197-88-5

Basic information

• Product Name: 1-ethynyl-2-phenoxybenzene
• Synonyms: 1-ethynyl-2-phenoxybenzene
• CAS NO: 512197-88-5
• Molecular Weight: 194.233
• Mol File: 512197-88-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-ethynyl-2-phenoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethynyl-2-phenoxybenzene(512197-88-5)
• EPA Substance Registry System: 1-ethynyl-2-phenoxybenzene(512197-88-5)

Safety Data

• Hazardous Substances Data: 512197-88-5(Hazardous Substances Data)

Upstream product

• 34883-46-0 1-(2-iodophenoxy)benzene 
• 994-89-8 tributylethynyltin 
• 324-02-7 2-phenoxybenzenediazonium tetrafluoroborate 
• 1027663-95-1 trimethyl[(2-phenoxyphenyl)ethynyl]silane 
• 2688-84-8 2-phenoxyaniline 
• 1028267-14-2 3-(2-phenoxy-phenyl)-prop-2-yn-1-ol 
• 108-95-2 phenol 
• 446-52-6 2-Fluorobenzaldehyde 
• 5256-74-6 1,3-diethyl 2-diazopropanedioate 
• 19434-34-5 2-(phenoxy)benzaldehyde 

Downstream Products

• 1379658-54-4 rac-5-(2-bromo-4-methylphenyl)-1-(2-phenoxyphenyl)pent-1-yn-3-ol 
• 1379658-96-4 1-(2-bromophenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-one 
• 1379658-85-1 (S)-1-(2-bromophenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-46-4 rac-1-(2-bromo-4-methylphenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-47-5 rac-1-(2-bromo-4-fluorophenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-48-6 rac-1-(2-bromo-4-(trifluoromethyl)phenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-49-7 rac-3-bromo-4-((2-hydroxy-4-(2-phenoxyphenyl)but-3-yn-1-yl)oxy)benzonitrile 
• 1379658-50-0 rac-1-(2-bromo-4-(tert-butyl)phenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-51-1 rac-1-(2-bromo-4-methoxyphenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-52-2 rac-1-((6-bromobenzo[d][1,3]dioxol-5-yl)oxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-45-3 rac-1-(2-bromophenoxy)-4-(2-phenoxyphenyl)but-3-yn-2-ol 
• 1379658-53-3 rac-5-(2-bromophenyl)-1-(2-phenoxyphenyl)pent-1-yn-3-ol 
• 112537-94-7 2,2,6,6-tetramethylpiperidin-1-yl diphenylphosphinate 

Relevant articles and documents

A metal-free radical cascade reaction of phosphine oxides with 2-aryloxy phenylacetylenes to synthesize diphosphonyl xanthene derivatives

A radical cascade reaction of 2-aryloxy phenylacetylenes with phosphine oxides promoted by K2S2O8was developed, which provided diphosphonyl xanthenes as products. This reaction proceeds under transition metal-free and mild conditions with simple operation and good yields. The mechanistic study indicated that phosphine oxide was induced into a phosphonyl radical, and then the following double radical addition/cyclization with 2-aryloxy phenylacetylenes generated bisphosphonyl xanthenes.

Synthesis of tetrasubstituted alkenes through a palladium-catalyzed domino carbopalladation/C-H-activation reaction

Helical tetrasubstituted alkenes (7) were obtained in a highly efficient way through a palladium-catalyzed domino-carbopalladation/CH-activation reaction of propargylic alcohols 6 in good to excellent yields. Electron-withdrawing- and electron-donating substituents can be introduced onto the upper and lower aromatic rings. The substrates (6) for the domino process were synthesized by addition of the lithiated alkyne (20) to various aldehydes (19); moreover, the substrates were accessible enantioselectively (in 95 % ee) by reduction of the corresponding ketone using the Noyori procedure. Copyright