51591-75-4 Usage
Description
CIS-1,3-DIBENZYL-2-OXO-4,5-IMIDAZOLIDINEDICARBOXYLIC ACID is an organic compound that serves as a crucial reagent in the total synthesis of Biotin. Biotin, also known as vitamin B7 or vitamin H, is a growth factor that plays an indispensable role in numerous naturally occurring carboxylation reactions. It is primarily found bound to proteins or polypeptides and is present in minute amounts in every living cell. The richest sources of Biotin include liver, kidney, pancreas, yeast, and milk. Interestingly, the biotin content of cancerous tumors is higher than that of normal tissue.
Uses
Used in Pharmaceutical Industry:
CIS-1,3-DIBENZYL-2-OXO-4,5-IMIDAZOLIDINEDICARBOXYLIC ACID is used as a reagent in the total synthesis of Biotin for its vital role in various biological processes. Biotin is essential for the production of certain fatty acids, the synthesis of certain amino acids, and the production of hormones and cholesterol. It also plays a crucial role in the metabolism of carbohydrates and the conversion of fats to energy.
Used in Nutritional Supplements:
CIS-1,3-DIBENZYL-2-OXO-4,5-IMIDAZOLIDINEDICARBOXYLIC ACID contributes to the production of Biotin, which is used as a nutritional supplement to support healthy skin, hair, and nails. Biotin deficiency can lead to hair loss, and its supplementation is believed to help maintain healthy hair and nails.
Used in Research and Development:
CIS-1,3-DIBENZYL-2-OXO-4,5-IMIDAZOLIDINEDICARBOXYLIC ACID is used as a reagent in the research and development of new drugs and therapies that target Biotin-dependent enzymes and pathways. This can lead to the discovery of novel treatments for various diseases and conditions, including cancer, where the biotin content is higher in tumor tissues compared to normal tissue.
Used in Diagnostic Applications:
CIS-1,3-DIBENZYL-2-OXO-4,5-IMIDAZOLIDINEDICARBOXYLIC ACID can be employed in the development of diagnostic tools and tests that measure Biotin levels in biological samples. This can help in the early detection of Biotin deficiency and monitor the effectiveness of Biotin supplementation in patients.
Check Digit Verification of cas no
The CAS Registry Mumber 51591-75-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,9 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 51591-75:
(7*5)+(6*1)+(5*5)+(4*9)+(3*1)+(2*7)+(1*5)=124
124 % 10 = 4
So 51591-75-4 is a valid CAS Registry Number.
InChI:InChI=1/C19H18N2O5/c22-17(23)15-16(18(24)25)21(12-14-9-5-2-6-10-14)19(26)20(15)11-13-7-3-1-4-8-13/h1-10,15-16H,11-12H2,(H,22,23)(H,24,25)/t15-,16+
51591-75-4Relevant articles and documents
Conversion method of 1, 3-dibenzyltetrahydro-4H-furo[3, 4-d]imidazole-2, 4(1H)dione
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Paragraph 0025-0057, (2019/05/16)
The invention discloses an oxidation conversion method of 1, 3-dibenzyltetrahydro-4H-furo[3, 4-d]imidazole-2, 4(1H)dione. The method includes: mixing 1, 3-dibenzyltetrahydro-4H-furo[3, 4-d]imidazole-2, 4(1H)-dione, an alkaline reagent and water, carrying out hydrolysis reaction till dissolved clarification, thus obtaining a hydrolysate with a pH value of 8.0-10.0; then mixing the hydrolysate witha nitrogen oxide and an oxidizing reagent for oxidation reaction, and finally performing post-treatment to obtain cis1,3-dibenzylimidazole-2-one-4, 5-dicarboxylic acid. The one-step oxidation conversion method provided by the invention has the characteristics of mild reaction conditions, simple operation, environmental friendliness and low equipment requirement, and the obtained product has high yield and low production cost, therefore the method is very suitable for industrialization and sustainable production of biotin, and has great practical application value and social and economic benefits.
Desymmetric hydrogenation of a meso-cyclic acid anhydride toward biotin synthesis
Yoshimura, Masahiro,Tsuda, Kazuomi,Nakatsuka, Hiroshi,Yamamura, Tomoya,Kitamura, Masato
scheme or table, p. 10006 - 10010 (2012/02/15)
Catalytic reactivity in the hydrogenation of a cyclic anhydride to a biotin synthetic intermediate has been investigated on the basis of Lyons' original method using Wilkinson Ru complex, revealing the high performance of DPPF and XANTPHOS diphosphines possessing wide bite angles. The results have shown a new trail for design of the corresponding asymmetric catalysts, and the potential utility of (S,S)-Et-FerroTANE and (S,S)-(R,R)-Ph-TRAP has been demonstrated.
Highly effective resolution of 1,3-dibenzyl-6-hydroxy-3,3a,6,6a-tetrahydroy-1H-furo[3,4-d]imidazole-2 ,4-dione, an intermediate for biotin, with optically active amines and reutilization of the unwanted epimer
Senuma,Fujii,Seto,Okamura,Date,Kinumaki
, p. 882 - 887 (2007/10/02)
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