51788-81-9

Basic information

• Product Name: 2-(2,4-Difluorophenyl)propan-2-ol
• Synonyms: 2-(2,4-Difluorophenyl)propan-2-ol;2,4-Difluoro-α,α-diMethyl-benzeneMethanol
• CAS NO: 51788-81-9
• Molecular Formula: C₉H₁₀F₂O
• Molecular Weight: 172.1719064
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 51788-81-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 216.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.182±0.06 g/cm3(Predicted)
• Solubility: Chloroform, Dichloromethane, Ether, Ethyl Acetate
• PKA: 13.95±0.29(Predicted)
• CAS DataBase Reference: 2-(2,4-Difluorophenyl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-Difluorophenyl)propan-2-ol(51788-81-9)
• EPA Substance Registry System: 2-(2,4-Difluorophenyl)propan-2-ol(51788-81-9)

Safety Data

• Hazardous Substances Data: 51788-81-9(Hazardous Substances Data)

Upstream product

• 348-57-2 2,4-difluorobromobenzene 
• 67-64-1 acetone 
• 364-83-0 2',4'-difluoroacetophenone 
• 75-16-1 methylmagnesium bromide 
• 106614-28-2 methyl 2,4-difluorobenzoate 
• 74-88-4 methyl iodide 

Downstream Products

• 156570-11-5 2-(2,4-Difluorophenyl)propene 

Relevant articles and documents

Native Amine-Directed ortho -C-H Halogenation and Acetoxylation /Condensation of Benzylamines

Free or unfunctionalized benzylamines are well known to participate in C-H activation in the presence of palladium salts. Despite the ease with which these complexes can be activated, subsequent functionalization of the dimeric cyclometalates can be chall

AZETIDINES AND CYCLOBUTANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS

The invention relates to compounds of formula (I) wherein R, R0, R1, m, n and X1 to X4 have the meaning as cited in the description and the claims. Said compounds are useful as Histamine H3 receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.