51865-84-0

Basic information

• Product Name: N-Formyl-4-(methylamino)benzoic acid
• Synonyms: N-FORMYL-4-(METHYLAMINO)BENZOIC ACID;4-(N-METHYL-N-FORMYLAMINO)BENZOIC ACID;N-FORMYL-4-(METHYLAMINO)BENZOIC ACID 98%;4-(N-Formylmethylamino)benzoic acid (FMABA);N-Formyl-4-(methylamino)benzoic acid,98%;4-[(2-oxoethyl)aMino]benzoic acid;4-(N-MethylforMaMido)benzoic acid;4-(ForMylMethylaMino)benzoic acid
• CAS NO: 51865-84-0
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.17
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 51865-84-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 217-221 °C
• Boiling Point: 311.69°C (rough estimate)
• Flash Point: 194.1 °C
• Appearance: WHITE TO LIGHT BEIGE POWDER
• Density: 1.2822 (rough estimate)
• Vapor Pressure: 5.02E-07mmHg at 25°C
• Refractive Index: 1.5600 (estimate)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-Formyl-4-(methylamino)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Formyl-4-(methylamino)benzoic acid(51865-84-0)
• EPA Substance Registry System: N-Formyl-4-(methylamino)benzoic acid(51865-84-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• Hazardous Substances Data: 51865-84-0(Hazardous Substances Data)

Usage

Chemical Properties

WHITE TO LIGHT BEIGE POWDER

InChI:InChI=1/C9H9NO3/c1-10(6-11)8-4-2-7(3-5-8)9(12)13/h2-6H,1H3,(H,12,13)/p-1

Upstream product

• 10541-83-0 N-methyl-p-aminobenzoic acid 
• 64-18-6 formic acid 

Relevant articles and documents

Process for the production of p-(N-methyl)-aminobenzoyl-L-glutamic acid

Process for the production of p-(N-methyl)-amino-benzoyl-L-glutamic acid. The process includes introducing a formyl group into p-(N-methyl)-amino-benzoic acid, with p-(N-methyl-N-formyl)-aminobenzoic acid being formed. The p-(N-methyl-N-formyl)-aminobenzoic acid is chlorinated with a chloridizing agent, such as, sulfonyl chloride or thionyl chloride, with p-(N-methyl-N-formyl)-aminobenzoic acid chloride forming. The p-(N-methyl-N-formyl)-aminobenzoic acid chloride is reacted with L-glutamic acid in the presence of a base as an acid acceptor, with p-(N-methyl-N-formyl)-amino benzoyl-L-glutamic acid forming. The p-(N-methyl-N-formyl)-amino benzoyl-L-glutamic acid is converted into p-(N-methyl)-amino benzoyl-L-glutamic acid by alkaline hydrolysis in a 2.5 to 3.5 normal caustic soda solution at 30° to 70° C. Intermediates which are obtained include: p-(N-methyl-N-formyl)-aminobenzoic acid; p-(N-methyl-N-formyl)-aminobenzoic acid chloride; and p-(N-methyl-N-formyl)-amino benzoyl-L-glutamic acid.