10541-83-0 Usage
Description
4-(Methylamino)benzoic acid, also known as PABA, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical products, dyes, flavors, and preservatives. It is a white to beige powder with significant applications across different industries due to its versatile chemical properties.
Uses
Used in Pharmaceutical Industry:
4-(Methylamino)benzoic acid is used as an intermediate for the production of medicines and other fine chemicals. It plays a vital role in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapeutic agents.
Used in Dye Industry:
In the dye industry, 4-(Methylamino)benzoic acid is used as a key component in the manufacturing process of various dyes. Its chemical properties allow for the creation of a wide range of colors and hues, making it an essential ingredient in the production of dyes for textiles, plastics, and other materials.
Used in Flavor and Fragrance Industry:
4-(Methylamino)benzoic acid is utilized as a building block for the development of flavors and fragrances. Its unique chemical structure enables the creation of distinct scents and tastes, which are used in the production of various consumer products, such as food, beverages, and cosmetics.
Used in Preservative Industry:
As a preservative, 4-(Methylamino)benzoic acid is used to extend the shelf life of products by inhibiting the growth of microorganisms. Its application in the preservation industry helps maintain the quality and safety of a wide range of products, including food, cosmetics, and pharmaceuticals.
References
https://www.alfa.com/en/catalog/A12426/
Check Digit Verification of cas no
The CAS Registry Mumber 10541-83-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,5,4 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10541-83:
(7*1)+(6*0)+(5*5)+(4*4)+(3*1)+(2*8)+(1*3)=70
70 % 10 = 0
So 10541-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2/c1-9-7-4-2-6(3-5-7)8(10)11/h2-5,9H,1H3,(H,10,11)/p-1
10541-83-0Relevant articles and documents
Preparation of 4-methylamino-benzoic acid from Anaesthesin (4-aminobenzoic acid ethyl ester) via phase-transfer methylation of its amino group
Skupinski,Pichnej,Pakula,et al.
, p. 862 - 864 (1986)
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Acetic Acid Accelerated Visible-Light Photoredox Catalyzed N-Demethylation of N,N-Dimethylaminophenyl Derivatives
Wu, Guolin,Li, Yazhen,Yu, Xuemei,Gao, Yu,Chen, Haijun
supporting information, p. 687 - 692 (2017/02/23)
N,N-Dimethylaminophenyl moiety is a common fragment in medicinal chemistry as several pharmaceuticals bearing this privileged motif are on the market and under clinical evaluation. Oxidative N-demethylation is generally regarded as the major metabolic pathway. However, pharmacokinetics, metabolites studies as well as the further structural modification are precluded by the impracticality of chemical synthesis. Here we report that acetic acid can significantly accelerate visible-light photoredox catalyzed N-demethylation of N,N-dimethylaminophenyl derivatives. This approach is easy for large scale reaction and even for potential industrial manufacture. (Figure presented.).
N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES
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Page/Page column 23, (2008/06/13)
The invention relates to N-thiazol-2-yl-benzamide derivatives of the formula I in the description wherein the variables are as defined in the claims. The compounds are A2A-receptor ligands, such as antagonists, agonists, reverse agonists or partial agonists, and are useful in the treatment of neurological and psychiatric disorders where an A2A-receptor is implicated.