52057-92-8

Basic information

• Product Name: 4-Chloro-2-anilinopyrimidine
• Synonyms: 4-Chloro-2-anilinopyrimidine
• CAS NO: 52057-92-8
• Molecular Formula: C₁₀H₈ClN₃
• Molecular Weight: 205.64
• Product Categories: pharmacetical
• Mol File: 52057-92-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Chloro-2-anilinopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-anilinopyrimidine(52057-92-8)
• EPA Substance Registry System: 4-Chloro-2-anilinopyrimidine(52057-92-8)

Safety Data

• Hazardous Substances Data: 52057-92-8(Hazardous Substances Data)

Upstream product

• 158661-55-3 2-Anilino-4-hydroxypyrimidine 
• 3934-20-1 2,6-Dichloropyrimidine 
• 62-53-3 aniline 
• 158661-55-3 2-(phenylamino)pyrimidin-4(3H)-one 

Downstream Products

• 110235-28-4 (4-methoxy-pyrimidin-2-yl)-phenyl-amine 
• 57356-49-7 phenyl-pyrimidin-2-yl-amine 
• 919836-53-6 4-(4-chloro-pyrimidin-2-ylamino)-benzenesulfonyl chloride 
• 1037622-38-0 4-[(4-chloropyrimidin-2-yl)amino]benzenesulphonyl chloride hydrochloride 
• 950752-51-9 4-(4-chloro-pyrimidin-2-ylamino)-N-cyclohexyl-benzenesulfonamide 

Relevant articles and documents

PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS

The invention provides novel pyridinamine-pyridone and pyrimidinamine- pyridone compounds of formula (I), pharmaceutical compositions containing such compounds, and methods for using such compounds in treatment of diseases including cancer, type II diabetes, inflammatory disease, neurodegenerative disorders, cardiovascular disorders, autoimmune diseases and viral infections; (I) wherein R1, R2, R3 and Z are as defined in the specification.

4-Aminoquinoline-Pyrimidine hybrids: Synthesis, antimalarial activity, heme binding and docking studies

A series of novel 4-aminoquinoline-pyrimidine hybrids has been synthesized and evaluated for their antimalarial activity. Several compounds showed promising in vitro antimalarial activity against both CQ-sensitive and CQ-resistant strains with high select

2-ANILINO-4-HETEROARYL PYRIMIDINE DERIVATIVES, AND PREPARATION THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS, AND IN PARTICULAR IKK INHIBITORS

The disclosure relates to a compound of formula (I): wherein R, R2, R3, R4, R5, z, D and W are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.