521-65-3

Basic information

• Product Name: swerchirin
• Synonyms: swerchirin;METHYLBELLIDIFOLIN;1,8-Dihydroxy-3,5-dimethoxy-9H-xanthen-9-one
• CAS NO: 521-65-3
• Molecular Formula: C15H12O6
• Molecular Weight: 288.254
• Mol File: 521-65-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 546.3°Cat760mmHg
• Flash Point: 210.6°C
• Appearance: /
• Density: 1.452g/cm³
• Vapor Pressure: 1.51E-12mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: swerchirin(CAS DataBase Reference)
• NIST Chemistry Reference: swerchirin(521-65-3)
• EPA Substance Registry System: swerchirin(521-65-3)

Safety Data

• Hazardous Substances Data: 521-65-3(Hazardous Substances Data)

Usage

Definition

ChEBI: A member of the class of xanthones that is the 5-O-methyl derivative of bellidifolin. Isolated from Centaurium erythraea and Swertia chirayita, it exhibits hypoglycemic activity.

InChI:InChI=1/C15H12O6/c1-19-7-5-9(17)12-11(6-7)21-15-10(20-2)4-3-8(16)13(15)14(12)18/h3-6,16-17H,1-2H3

Upstream product

• 26674-36-2 1-(β-D-glucopyranosyloxy)-8-hydroxy-3,5-dimethoxy-9H-xanthen-9-one 
• 186581-53-3 diazomethane 
• 2980-32-7 1,3,5,8-tetrahydroxyxanthone 
• 1444411-77-1 1-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl]-8-hydroxy-3,5-dimethoxyxanthone 

Downstream Products

• 2980-32-7 1,3,5,8-tetrahydroxyxanthone 
• 5557-27-7 1,3,5-Trimethoxy-8-hydroxyxanthone 
• 49599-09-9 1,8-dihydroxy-3,5,8-trimethoxyxanthone 

Relevant articles and documents

Xanthone glycoside constituents of Swertia kouitchensis with α-glucosidase inhibitory activity

Ten new xanthone glycosides, kouitchensides A-J (1-10), and 11 known analogues were isolated from an n-butanol fraction of Swertia kouitchensis. The structures of these glycosides were determined on the basis of extensive spectroscopic data interpretation and comparison with data reported in the literature. In an in vitro test, compounds 2, 4, 5, 6, 11, 12, and 13 (IC 50 values in the range 126 to 451 μM) displayed more potent inhibitory effects against α-glucosidase activity than the positive control, acarbose (IC50 value of 627 μM).