524-80-1

Basic information

• Product Name: CARBAZOL-9-YL-ACETIC ACID
• Synonyms: TIMTEC-BB SBB010077;CARBAZOL-9-YL-ACETIC ACID;9-CARBAZOLEACETIC ACID;(9-carbazolyl)acetic acid;(9-Carbazolyl)acetic acid, 9-(Carboxymethyl)carbazole;2-(9H-Carbazole-9-yl)acetic acid;9H-Carbazole-9-acetic acid;N,N-Diphenyleneglycine
• CAS NO: 524-80-1
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.24
• Mol File: 524-80-1.mol
• Article Data: 15

Chemical Properties

• Melting Point: 191-194 °C
• Boiling Point: 366.75°C (rough estimate)
• Flash Point: 188.2 °C
• Appearance: /
• Density: 1.1508 (rough estimate)
• Vapor Pressure: 1.06E-06mmHg at 25°C
• Refractive Index: 1.5780 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.13±0.10(Predicted)
• Merck: 13,1798
• BRN: 190299
• CAS DataBase Reference: CARBAZOL-9-YL-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: CARBAZOL-9-YL-ACETIC ACID(524-80-1)
• EPA Substance Registry System: CARBAZOL-9-YL-ACETIC ACID(524-80-1)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 524-80-1(Hazardous Substances Data)

Usage

Purification Methods

Crystallise the acid from ethyl acetate. [Fan et al. Anal Chim Acta 367 1 1998, Beilstein 20 III/IV 3841.]

InChI:InChI=1/C14H11NO2/c16-14(17)9-15-12-7-3-1-5-10(12)11-6-2-4-8-13(11)15/h1-8H,9H2,(H,16,17)

Upstream product

• 6209-23-0 2-(9H-carbazole-9-yl) acetic acid ethyl ester 
• 86-74-8 9H-carbazole 
• 79-08-3 bromoacetic acid 
• 79-11-8 chloroacetic acid 
• 143948-85-0 N-((methoxycarbonyl)methyl)carbazole 
• 105-36-2 ethyl bromoacetate 
• 105-39-5 chloroacetic acid ethyl ester 
• 33650-06-5 sodium salt of carbazole 
• 7748-25-6 potassium chloroacetate 

Downstream Products

• 1484-12-4 N-methylcarbazole 
• 148582-31-4 9-<(((3-((((benzyloxy)carbonyl)amino)methyl)benzyl)amino)carbonyl)methyl>carbazole 
• 148582-32-5 9-<(((3-(aminomethyl)benzyl)amino)carbonyl)methyl>carbazole 
• 1219733-91-1 C₃₂H₃₁N₅O₅ 
• 937269-47-1 (triphenylphosphine)2Ag(N-carbazolylacetic acid-H) 
• 1449415-35-3 C₃₈H₃₅N₅O₅ 

Relevant articles and documents

Biocompatible small peptide super-hydrogelators bearing carbazole functionalities

For the first time we have introduced carbazole capping groups onto two short peptide sequences, namely a diphenylalanine dipeptide and a glycine-diphenylalanine tripeptide, giving compounds 1 and 2, respectively. Both molecules form hydrogels at low concentrations, as low as 0.03% (w/v) for 1 - well within the range of supergelators. Both gelators are composed of small ca. 2 nm thick molecular fibres, as elucidated by AFM and are non-cytotoxic towards HeLa cells at concentrations which are at or above their minimum gelation concentration.

Tricyclic heterocycles display diverse sensitivity to the A147T TSPO polymorphism

The 18 kDa translocator protein (TSPO) is a target for the development of imaging agents to detect neuroinflammation. The clinical utility of second-generation TSPO ligands has been hindered by the presence of a polymorphism, rs6971, which causes a non-co

N of a kind of preparation method of-carbencillin methyl carbazole

The invention relates to a method for preparing N-carboxymethylcarbazole. The method comprises the steps of directly mixing carbazole, potassium acetate and N, N-dimethylformamide, then, heating and regulating the pH value to 8-9 in heating; then, cooling the reaction solution, and regulating the solution to be strong acid; and next, adding the solution into water to obtain N-carboxymethylcarbazole. According to the invention, N-carboxymethylcarbazole is obtained by taking carbazole and potassium acetate as raw materials through one-step synthesis; the method is short in reaction time, simple in reaction process, easy to operate, very high in raw material conversion rate and high in product yield (more than 95%); and the novel design thought provides more application space for the synthesis of N-carboxymethylcarbazole.