52458-11-4 Usage
Derivative of
Bromobenzene
Functional groups
Benzyl ether group, t-butyl group
Attached to
1-position (benzyl ether), 4-position (t-butyl)
Common use
Organic synthesis reagent
Specific reactions
Suzuki coupling, Heck reaction
Building block for
Pharmaceuticals, agrochemicals, fine chemicals
Physical state
Colorless to pale yellow liquid
Solubility
Insoluble in water, soluble in organic solvents (ethanol, ether)
Hazardous nature
Potential for skin, eye, and respiratory tract irritation
Check Digit Verification of cas no
The CAS Registry Mumber 52458-11-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,5 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 52458-11:
(7*5)+(6*2)+(5*4)+(4*5)+(3*8)+(2*1)+(1*1)=114
114 % 10 = 4
So 52458-11-4 is a valid CAS Registry Number.
52458-11-4Relevant articles and documents
Research on unique masked ortho-benzoquinone, monohemiaminal: Synthesis and reactions
Matsumoto, Yuri,Nakamura, Akihiko,Saito, Emi,Nakada, Masahisa
, p. 232 - 252 (2019/04/27)
Synthesis of ortho-benzoquinone monohemiaminals via the oxidative dearomatization/O-cyclization cascades of phenols bearing an ortho substituent derived from an amino alcohol with PIDA is described. The cascade reactions of substrates bearing a chiral substituent were found to proceed in a stereoselective manner. The Diels-Alder reactions of the ortho-benzoquinone monohemiaminals proceed in a highly stereoselective manner. The oxidative dearomatization/O-cyclization cascade affording the ortho-benzoquinone monohemiaminal had never been reported; hence, there is still ample scope for further investigation.
