528-93-8

Basic information

• Product Name: SILVER SALICYLATE
• Synonyms: SILVER SALICYLATE;Silver salicylate hydrate;Salicylic acid silver(I) salt;Nsc408900;Silver salicylate, ag(C7H5o3);silver(I) 2-hydroxybenzoate
• CAS NO: 528-93-8
• Molecular Formula: Ag*C₇H₅O₃
• Molecular Weight: 244.98
• EINECS: 200-712-3
• Mol File: 528-93-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 336.3°C at 760 mmHg
• Flash Point: 144.5°C
• Appearance: /
• Density: 1.375g/cm³
• Vapor Pressure: 4.45E-05mmHg at 25°C
• Refractive Index: 1.615
• Water Solubility: Soluble in water (0.95 mg/ml at 23°C).
• Sensitive: Light Sensitive
• CAS DataBase Reference: SILVER SALICYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: SILVER SALICYLATE(528-93-8)
• EPA Substance Registry System: SILVER SALICYLATE(528-93-8)

Safety Data

• Hazardous Substances Data: 528-93-8(Hazardous Substances Data)

Usage

General Description

Silver salicylate is a chemical compound consisting of silver, carbon, hydrogen, and oxygen elements and has the chemical formula C14H8Ag2O6. SILVER SALICYLATE is majorly utilized for its antibacterial properties in the medical field. It exhibits the characteristics of both its constituent elements – the antimicrobial property of silver and the anti-inflammatory, analgesic property of salicylate (derived from salicylic acid - an organic acid used in numerous healthcare products). In its pure form, it appears as a grey or white solid substance. Despite its advantageous properties, caution is required in its usage due to the potential toxicity of silver in high concentrations.

InChI:InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

Upstream product

• 69-72-7 salicylic acid 
• 62-53-3 aniline 
• 54-21-7 sodium salicylate 
• 50-78-2 aspirin 

Downstream Products

• 133-91-5 3,5-diiodosalicylic acid 
• 20210-97-3 ethane-1,2-diyl bis(2-hydroxybenzoate) 
• 71797-18-7 O²,O³,O⁴-triacetyl-O¹-salicyloyl-β-D-glucopyranuronic acid methyl ester 
• 73960-72-2 methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate 
• 82703-91-1 Benzyl-2,3,4-tri-O-benzyl-6-O-(methyl-5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-didesoxy-D-glycero-α-D-galacto-2-nonulopyranosylonat)-β-D-galactopyranosid 
• 82703-92-2 methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-O-salicyoyl-D-galacto-2-nonulopyranoside 
• 82703-90-0 (2S,4S,5R,6R)-5-Acetylamino-4-hydroxy-2-((2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethoxy)-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 5094-26-8 2-hydroxybenzoylcholine 
• 88962-61-2 (S)-2-[(S)-2-Benzyloxycarbonylamino-3-((3aR,5R,6R,7S,7aR)-6,7-diacetoxy-5-acetoxymethyl-2-methyl-tetrahydro-[1,3]dioxolo[4,5-b]pyran-2-yloxy)-propionylamino]-4-methyl-pentanoic acid 2-chloro-ethyl ester 
• 88962-58-7 N-Benzyloxycarbonyl-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-L-seryl-L-leucin-2-chlorethylester 
• 33019-34-0 2-[(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzoic acid 
• 82703-93-3 benzyl 2,3,4-tri-O-benzyl-6-O-(methyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate)-β-D-galactopyranoside 
• 132608-97-0 Sn(C₆H₅)2(C₅H₅)OOCC₆H₄OH 

Relevant articles and documents

Ultrasonic accelerated efficient synthesis of aminobenzochromenes using Ag2Cr2O7 nanoparticles as a reusable heterogeneous catalyst

Ag2Cr2O7 nanoparticles were found to be an exceedingly effective catalyst for the mild and green synthesis of aminobenzochromenes. The reaction was performed under ultrasonic irradiation as an innocuous tool and in water a

Novel mixed metal Ag(I)-Sb(III)-metallotherapeutics of the NSAIDs, aspirin and salicylic acid: Enhancement of their solubility and bioactivity by using the surfactant CTAB

The already known Ag(I)-Sb(III) compound of the formula {Ag(Ph3Sb)3(NO3)} (1) and two novel mixed metal Ag(I)-Sb(III) metallotherapeutics of the formulae {Ag(Ph3Sb)3(SalH)}(2) and {Ag(Ph3Sb)3(Asp)}(3) (SalH2 = salicylic acid, AspH = aspirin or 2-acetylsalicylic acid and Ph3Sb = triphenyl antimony(III)) have been synthesised and characterised by m.p., vibrational spectroscopy (mid-FT-IR), 13C-,1H-NMR, UV-visible (UV-vis) spectroscopic techniques, high resolution mass spectroscopy (HRMS) and X-ray crystallography. Compounds 1,- 3 were treated with the surfactant cetyltrimethylammonium bromide (CTAB) in order to enhance their solubility and as a consequence their bioactivity. The resulting micelles a-c were characterised with X-ray powder diffraction (XRPD) analysis, X-ray fluorescence (XRF) spectroscopy, Energy-dispersive X-ray spectroscopy (EDX), conductivity, Thermal gravimetry-differential thermal analysis (TG-DTA), and atomic absorption. Compounds 1-3 and the relevant micelles a-c were evaluated for their in vitro cytotoxic activity against human cancer cell lines: MCF-7 (breast, estrogen receptor (ER) positive), MDA-MB-231 (breast, ER negative) and MRC-5 (normal human fetal lung fibroblast cells) with sulforhodamine B (SRB) colorimetric assay. The results show significant increase in the activity of micelles compared to that of the initial compounds. Moreover, micelles exhibited lower activity against normal cells than tumor cells. The binding affinity of a-c towards the calf thymus (CT)-DNA, lipoxygenase (LOX) and glutathione (GSH) was studied by the fluorescent emission light and UV-vis spectroscopy.

Synthesis and characterization of AgSCN micro/nanostructures by sonochemical method

Silver (I) salicylate complex marked as [Ag(HSal)] was prepared, characterized, and applied to fabricate AgSCN micro/nanostructures. The [Ag(HSal)] complex was synthesized by silver nitrate and sodium salicylate via a simple precipitation route. To obtain AgSCN micro/nanostructures, the [Ag(HSal)] complex and KSCN were mixed with molar ratio of 1:1 in the presence of ultrasound irradiation. Besides, the effect of sonication time and surfactant on the morphology and particle size of the products was investigated. In this work, polyvinyl pyrrolidone was used as surfactant to prepare star-like and flower-like AgSCN microstructures. The products were analyzed by FT-IR, XRD, EDS, SEM, and TEM.