5293-42-5Relevant articles and documents
Improved Julia-Kocienski conditions for the methylenation of aldehydes and ketones
Aissa, Christophe
, p. 360 - 363 (2007/10/03)
The scope of the methylenation of aldehydes and ketones under optimized Julia-Kocienski conditions is broadened by using 1-tert-butyl-1H-tetrazol-5- ylmethyl sulfone. Two different Barbier-type procedures are applied with NaHMDS at -78 °C or Cs2CO3 at 70 °C. The latter conditions are also adapted for the preparation of 1,2-disubstituted olefins and intramolecular olefination reactions.
Total synthesis of the ravidomycin aglycone (defucogilvocarcin V)
Findlay, John A.,Daljeet, Anand,Murray, Peter John,Rej, Rabindra N.
, p. 427 - 431 (2007/10/02)
The synthesis of 1-hydroxy-10,12-dimethoxy-8-vinyl-6H-benzonaphtho-pyran-6-one 7, starting from vanillin and 1,5-dihydroxynaphthalene is described.This compound is the aglycone of the antitumor antibiotic ravidomycin and is identical with the recently reported antimicrobial agent, defucogilcocarcin V.